Botswana Pediatric Respiratory Disease and Bloodstream Infection Study

Completed

• Conditions: HIV Infections; Respiratory Tract Diseases; Sepsis

• Registration Number: NCT00197691
• Lead Sponsor: Harvard School of Public Health (HSPH)

Brief Summary

The purpose of this study is to learn about lower respiratory tract and bloodstream diseases among infants born to HIV positive mothers in Botswana. Study factors include how commonly infants get these diseases, the causes, and outcomes. The study will also try to measure the protective effect, if any, of breast feeding on respiratory disease illness and deaths.

Detailed Description

Not available

Study Timeline

• Study Start: 2001-03
• Study First Submitted: 2005-09-13
• Study First Submitted QC: 2005-09-13
• Study First Posted: 2005-09-20
• Primary Completion: 2005-10
• Study Completion: 2005-10
• Status Verified: 2012-03
• Last Update Submitted: 2012-03-30
• Last Update Posted: 2012-04-02

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: Not specified

Inclusion Criteria

• Participation in parent study, "Mashi" HIV vertical transmission prevention study for pregnant Botswana women and their infants

Exclusion Criteria

Not provided

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
OCCURRENCE OF SUSPECTED PNEUMONIA OR BLOODSTREAM INFECTION OVER FIRST TWO YEARS OF LIFE	Between birth and 2 years of life	MORTALITY; EPISODES OF SUSPECTED PNEUMONIA; BACTEREMIA; PRESENCE OF NASOPHARYNGEAL VIRAL PATHOGENS; OROPHARYNGEAL COLONIZATION WITH BACTERIAL PATHOGENS

Trial Locations

Locations (1)

Princess Marina Hospital; 🇧🇼 Gaborone, Botswana