Brain Mechanisms of Reducing Polysubstance Use Following a Novel Body-mind Intervention 2
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Multiple Drug Use
- Sponsor
- Arizona State University
- Enrollment
- 35
- Locations
- 1
- Primary Endpoint
- Intervention effects on brain grey matter using fMRI
- Status
- Recruiting
- Last Updated
- last year
Overview
Brief Summary
The proposed study will test whether neurofeedback (NF) could optimize integrative body-mind training (IBMT) practice.
Detailed Description
The proposed study will test whether real-time NF could optimize IBMT practice and improve effects in reducing polysubstance use through targeting self-control networks in the brain.
Investigators
Eligibility Criteria
Inclusion Criteria
- •At least 18 years old
- •Free of any psychiatric diagnoses or medication (besides a substance use disorder (SUD) to alcohol, tobacco, or cannabis)
- •In the past month, at least 4 episodes of heavy episodic drinking; at least 3 occasions of cannabis use; and daily cigarette use for at least the past month
- •Normal or corrected-to-normal vision
- •Written informed consent
- •No previous meditation or NF experiences
Exclusion Criteria
- •Any psychiatric diagnoses other than an SUD
- •Medical disorder(s) that may affect the central nervous system; medications that affect the central and autonomic nervous system; or a positive pregnancy test result (females)
- •Excluding cannabis, evidence of recent (past month) illicit drug use
Outcomes
Primary Outcomes
Intervention effects on brain grey matter using fMRI
Time Frame: The outcome measures are assessed in-person at baseline, 2-4 weeks and 3 months
Brain volume changes such as anterior and posterior cingulate cortex measured by fMRI structural imaging
Intervention effects on brain white matter using fMRI
Time Frame: The outcome measures are assessed in-person at baseline, 2-4 weeks and 3 months
Brain white matter changes such as anterior and posterior cingulate cortex measured by fMRI diffusion tensor imaging
Intervention effects on brain function using Functional Magnetic Resonance Imaging (fMRI)
Time Frame: The outcome measures are assessed in-person at baseline, 2-4 weeks and 3 months
Brain connectivity changes such as anterior and posterior cingulate cortex measured by fMRI resting state imaging
Secondary Outcomes
- Intervention effects on addiction behavior using substance use questionnaires in PhenX Toolkit(The outcome measures are assessed in-person at baseline, 2-4 weeks and 3 months)