Skip to main content
Clinical Trials/NCT07332624
NCT07332624
Enrolling By Invitation
Not Applicable

Instant Message-delivered Acceptance and Commitment Therapy (ACT) for Neuropsychiatric Symptoms in Persons Living With Mild Cognitive Impairment: a Pilot Randomised Controlled Trial

The University of Hong Kong1 site in 1 country40 target enrollmentStarted: September 17, 2025Last updated:

Overview

Phase
Not Applicable
Status
Enrolling By Invitation
Enrollment
40
Locations
1
Primary Endpoint
MBI-C scores

Overview

Brief Summary

This pilot study aims to develop an automated instant message-delivered intervention (i.e., EMI) for people with mild cognitive impairment, and to investigate the feasibility and effectiveness of the intervention.

Detailed Description

  1. Message contents: The message content library will consist of two parts: 1. brief mild cognitive impairment messages (optional), and 2. acceptance and commitment therapy messages (mandatory).
  2. Message delivery
  • Regular messages: The messages in the two parts will be sent regularly to each participant. As personalisation is a core process subject to behavioural changes, the content, frequency, and timing of the messages will be determined based on participants' preferences. To save labour and increase efficiency, we will develop a message 'scheduler' program. We will pre-set the message scheduler, which will then automatically send out content to participants according to their preferences. The development of the program is highly useful particularly in cases which participants prefer to receive messages during non-office hours.
  • Therapist-led real-time support messages (chat-type): Chat-based support will be given to the participants as an extension of the regular messages. However, the participants will be informed beforehand that the RA will only play a supportive role and will not provide formal care. The number of the chat messages will not be limited, but the real-time support messages will only be provided during working hours (i.e., 9am-6pm) on weekdays to limit the RA's workload.

Control Group:

The control group will receive instant messages about mental health management from HKSAR Government website (https://www.shallwetalk.hk/en/mental-well-being/mental-well-being-is-related-to-you/), which is open to the public.

Study Design

Study Type
Interventional
Allocation
Randomized
Intervention Model
Parallel
Primary Purpose
Supportive Care
Masking
Double (Participant, Investigator)

Eligibility Criteria

Ages
50 Years to — (Adult, Older Adult)
Sex
All
Accepts Healthy Volunteers
No

Inclusion Criteria

  • Community-dwelling adults aged ≥ 50 years; HK-MoCA score range from 18 to 25; MBI-C ≥7; Able to read and communicate in Chinese (Cantonese or Putonghua); Able to use the text or voice messaging function on a smartphone.

Exclusion Criteria

  • Diagnosis of dementia; Diagnosis of psychiatric disease; Currently participating in any type of psychological or behavioural intervention for NPSs

Arms & Interventions

Intervention group

Experimental

Participants in intervention group will receive the EMI for 8 weeks. Based on the steps of mobile message development recommended by Abroms, et al., our team will develop an ACT message content library and protocol for IM delivery (i.e. EMI).

Intervention: Automated instant message-guided neuropsychiatric symptoms management (Behavioral)

Control group

No Intervention

The control group will receive instant messages about general mental health management from the HKSAR Government website, which is open to the public (https://www.shallwetalk.hk/en/mental-well-being/mental-well-being-is-related-to-you/), with reminder text messages of follow-up surveys.

Outcomes

Primary Outcomes

MBI-C scores

Time Frame: 8 weeks

The primary outcome will be MBI-C scores to assess NPSs. A higher MBI-C scores will indicate a higher level of neuropsychiatric symptoms.

Secondary Outcomes

  • Depressive symptoms (PHQ-9)(8 weeks)
  • Anxiety symptoms (GAD-7)(8 weeks)
  • Cognitive functions (HK-MoCA)(8 weeks)
  • Acceptance of negative emotions and valued-based actions (AAQ-II)(8 weeks)

Investigators

Sponsor Class
Other
Responsible Party
Sponsor

Study Sites (1)

Loading locations...

Similar Trials