Failure of non-invasive intermittent positive pressure ventilatio
Not Applicable
- Conditions
- Health Condition 1: P220- Respiratory distress syndrome of newborn
- Registration Number
- CTRI/2024/04/066151
- Lead Sponsor
- Dr Sonali Amol Avale
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
•Gestational age (GA) between 26 and less than 37 weeks weeks. GA will be determined by dates or a dating ultrasound.
•Clinical and radiological Diagnosis of RDS -The diagnosis of RDS will be based on clinical manifestations (tachypnea, nasal flaring, and or grunting and chest Xray suggestive of RDS
Exclusion Criteria
1.Any baby intubated for resuscitation or for other reasons.
2. Major congenital malformations or known complex congenital heart disease
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To study incidence, risk factors of noninvasive intermittent positive pressure ventilation (NIPPV) failure, defined as the need for intubation within 72 hours of lifeTimepoint: First 72 hours of life
- Secondary Outcome Measures
Name Time Method 1.Days of hospitalization, <br/ ><br>2.Days on NIV, <br/ ><br>3.Days on supplemental oxygen, <br/ ><br>4.Pre-discharge mortality, <br/ ><br>5.Surfactant doses, <br/ ><br>6.Retinopathy of prematurity, <br/ ><br>7.Bronchopulmonary dysplasia , <br/ ><br>8.Abdominal distention, feed intolerance, time to full feed, air leaks <br/ ><br>9. Intraventricular hemorrhage , <br/ ><br>10.Spontaneous intestinal perforation, <br/ ><br>11.Presence of thick secretions causing an airway obstructionTimepoint: Death <br/ ><br>Discharge