Correlation Between Respiratory Variability of R-R Intervals and Systolic Pressure Variability

• Conditions: Heart Rate Determination
• Interventions: Other: posture changes

• Registration Number: NCT03267017
• Lead Sponsor: Rambam Health Care Campus

Brief Summary

This prospective study is designed to assess and quantify the correlation between respiratory changes in R-R interval and the respiratory changed in invasive systolic blood pressure in ventilated patients during changes in posture and peak end expiratory pressure (PEEP) and following a fluid bolus

Detailed Description

Not available

Study Timeline

• Status Verified: 2017-08
• Study First Submitted: 2017-08-28
• Study First Submitted QC: 2017-08-29
• Last Update Submitted: 2017-08-29
• Study First Posted: 2017-08-30
• Last Update Posted: 2017-08-30
• Study Start: 2017-11-01
• Primary Completion: 2018-11-01
• Study Completion: 2019-05-01

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 40

Inclusion Criteria

• Age 18-80
• Scheduled for surgery under general anesthesia requiring invasive blood pressure monitoring

Exclusion Criteria

• Heart Rate other than sinus
• Cardiac Pacemaker Status
• Transplanted Heart

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Patient scheduled for surgery under general anesthesia	posture changes	-

Primary Outcome Measures

Name	Time	Method
Statistical Correlation between respiratory variability of R-R interval and systolic blood pressure	From immediately after induction of general anesthesia and mechanical ventilation to 20 minutes later