Perineural versus IV dexmedetomidine with adductor canal block for perioperative analgesia in total knee arthroplasty; a randomized prospective controlled study
Not Applicable
Recruiting
- Conditions
- Anaesthesia
- Registration Number
- PACTR202006770945823
- Lead Sponsor
- Rabab Mahrous
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 100
Inclusion Criteria
American Society of Anesthesiologists (ASA) physical status I or II
Patient scheduled for total knee arthroplasty
Exclusion Criteria
BMI > 35 kg/m2,
pregnancy/lactation,
any cardiac comorbidity,
pre-existing neurological deficit,
significant renal or hepatic impairment,
severe pulmonary compromise,
known contraindications to peripheral nerve block,
allergies to local anaesthetic or dexmedetomidine, or
chronic opioid users/abusers.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method compare the duration of analgesia provided by ultrasound-guided adductor canal block (ACB) with either the addition of dexmedetomidine to the block or given intravenously (IV) intraoperatively in total knee replacement surgery.
- Secondary Outcome Measures
Name Time Method Intraoperative and postoperative hemodynamics (MAP and HR), total analgesic (morphine) consumption, postoperative Ramsay sedation score, resting visual analogue scale (VAS), and dynamic VAS.