The efficacy of prophylactic antibiotics in the management of pneumonitis following paraffin ingestion in childre

Not Applicable

• Conditions: Injury, Occupational Diseases, Poisoning; Respiratory; Paediatrics; paraffin poisoning

• Registration Number: PACTR201201000259370
• Lead Sponsor: Dr Kate Balme

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2010-10-28
• Last Update Posted: 29 May 2023

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 200

Inclusion Criteria

Ingested paraffin in the preceding 24 hours
Presence of respiratory symptoms or signs
Informed consent by parent/legal guardian
Resident within the hospital drainage area and able to come for 2 follow up appointments

Exclusion Criteria

1. Asymptomatic and no clinical signs
2. Too ill to be excluded from receiving an antibiotic as judged by:
o Requiring more than 2L/min nasal-prong oxygen
o Requiring continuous or intermittent positive airway pressure ventilation
o Fever > 40 degrees Celsius
3. Needing an antibiotic for another reason e.g. otitis media, tonsillitis
4. Current antibiotic use, prior to kerosene ingestion
5. Allergic to amoxicillin

Study & Design

• Study Type: Interventional
• Study Design: Not specified