The use of ultraviolet light photochemotherapy Polarised Ultra Violet A [PUVA] in the oral cavity in conjunction with a oral photo-sensitiser [5-methoxypsolaren or 8-methoxypsoralen] for oral graft-versus- host disease [GVHD] in allogeneic bone marrow transplant patients [ABMT].
Phase 1
Recruiting
- Conditions
- Chronic Oral Graft versus Host DiseaseBlood - Haematological diseases
- Registration Number
- ACTRN12613000330741
- Lead Sponsor
- St Vincent's Hospital, Sydney
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 25
Inclusion Criteria
Undergone Allogeneic Stem cell transplant with clinical diagnosis of oral GVHD and any degree or oral symptoms leading to pain, discomfort and interfere with oral intake.
Histological confirmation not required.
Exclusion Criteria
Sensivity to sunscreens and photosensitisers.
Known photodermatoses.
Foreseeable intense exposure to solar or UV exposure except study related.
unable to take tablets
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method