Observation of Long Term Effect of Medical and PTPA Treatment on Patients With Takayasu Arteritis Complicated With Pulmonary Artery Involvement
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 发起方
- 入组人数
- 200
- 试验地点
- 1
- 主要终点
- mean pulmonary arterial pressure change
研究概览
简要总结
- Evaluate the effect of medical treatment and percutaneous transluminal pulmonary angioplasty on takayasu arteritis with pulmonary artery involvement
- evaluate the efficacy of FAPI in predicting the activity and treatment efficacy of takayasu arteritis with pulmonary artery involvement
详细描述
At baseline, FAPI and FDG are performed to evaluate the activity of takayasu arteritis with pulmonary artery involvement. FAPI is also used to predict the treatment efficacy and prognosis of takayasu arteritis with pulmonary artery involvement.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •patients diagnosed with Takayasu arteries with pulmonary arteries involvement
排除标准
- •Patients had pulmonary artery stenosis arising from CTEPH, fibrosing mediastinitis and congenital pulmonary artery stenosis
结局指标
主要结局
mean pulmonary arterial pressure change
时间窗: 2014/1/1-2042/12/31
change of mean pulmonary arterial pressure after treatment
pulmonary vascular resistance change
时间窗: 2014/1/1-2042/12/31
chagne of pulmonary vascular resistance after treatment
peak VO2 change
时间窗: 2014/1/1-2042/12/31
change of peak oxygen consumption after treatment
NT-proBNP change
时间窗: 2014/1/1-2042/12/31
change of NT-proBNP after treatment
all cause death
时间窗: 2014/1/1-2042/12/31
all cause death
6MWD change
时间窗: 2014/1/1-2042/12/31
change of six minute walk distance after treatment
CI change
时间窗: 2014/1/1-2042/12/31
change of cardiac index after treatment
RV/LV change
时间窗: 2014/1/1-2042/12/31
change of right ventricular end-diastolic diameter versus laboratory left ventricular end-diastolic diameterafter treatment
次要结局
未报告次要终点