Effect of Adding Magnesium Sulphate in Pericapsular Nerve Group Block

Phase 2

Not yet recruiting

• Conditions: Hip Fractures
• Interventions: Drug: Pericapsular nerve group block using bupivicaine and magnesium sulphate

• Registration Number: NCT06180031
• Lead Sponsor: Assiut University

Brief Summary

Our aim will be to compare the analgesic efficacy and safety of magnesium sulphate as an adjuvant to bupivacaine in pericapsular nerve group block in Hip joint surgeries.

* Our primary outcome of the study: total amount of postoperative morphine consumption in the first 24h postoperative.

* Our secondary outcome of the study: mean arterial blood pressure, heart rate, respiratory rate, adverse effects, block related complication, sedation score (by Ramsay sedation scale) and pain score (by Visual Analog Scale)

Detailed Description

Not available

Study Timeline

• Status Verified: 2023-12
• Study First Submitted: 2023-12-02
• Study First Submitted QC: 2023-12-21
• Last Update Submitted: 2023-12-21
• Study First Posted: 2023-12-22
• Last Update Posted: 2023-12-22
• Study Start: 2024-01-01
• Primary Completion: 2025-01-01
• Study Completion: 2025-03-30

Recruitment & Eligibility

• Status: NOT_YET_RECRUITING
• Sex: All
• Target Recruitment: 62

Inclusion Criteria

• • Patients aged 18 years or more.

  • Patients with American society of anesthesiologists (ASA) classification class I or II
  • Patients weight range from 50 to 90 Kgs

Exclusion Criteria

• • Patient refusal of peripheral nerve block

  • Patient with infection at the site of injection
  • Patient with coagulopathy
  • Patients with known allergy to used medications.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Group M	Pericapsular nerve group block using bupivicaine and magnesium sulphate	will have PENG block with 2mg magnesium sulphate 10% as an adjuvant to 20mg of bupivacaine 0.25%

Primary Outcome Measures

Name	Time	Method
Postoperative pain management	24 hours postoperatively	total amount of postoperative morphine consumption in the first 24 hours postoperatively.

Secondary Outcome Measures

Name	Time	Method
Visual analog scale	24 hours postoperatively	It's a scale from 0 to 10 where 0 means no pain and 10 means worst pain imaginable

Trial Locations

Locations (1)

Assiut University Hospital; 🇪🇬 Assiut, Egypt