EVALUATING EFFICACY OF PLATELET RICH PLASMA, INJECTABLE PLATELET RICH FIBRIN AND GROWTH FACTOR CONCENTRATE ON PROMOTING HAIR REGROWTH: A CLINICAL TRIAL
试验速览
- 阶段
- 2 期
- 状态
- 尚未招募
- 发起方
- 入组人数
- 21
- 试验地点
- 1
- 主要终点
- GFC is better than other blood components in Hair Regrowth
研究概览
简要总结
Androgenic alopecia (AGA) is the most common form of hair loss, influenced by genetics and androgens like DHT. It presents as patterned hair loss in men and diffuse thinning in women, known as Female Pattern Hair Loss (FPHL). Conventional treatments include oral finasteride and topical minoxidil but may cause side effects and inconsistent results. Hair transplants offer a solution but are expensive and may require multiple sessions. Autologous platelet concentrates are gaining attention for their regenerative properties. PRP (Platelet-Rich Plasma) is rich in growth factors that stimulate hair follicle activity and scalp regeneration. iPRF (Injectable Platelet-Rich Fibrin) offers a more bioactive and sustained release of growth factors compared to PRP. GFC (Growth Factor Concentrate) uses activated platelets to enhance vascularization and follicular repair. These therapies aim to improve hair growth, density, and follicular health in AGA patients. A comparative study is needed to determine which therapy is most effective, safe, and yields faster results.
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研究设计
- 研究类型
- Interventional
- 分配方式
- Computer generated randomization
- 盲法
- Not Applicable
入排标准
- 年龄范围
- 18.00 Year(s) 至 45.00 Year(s)（—）
- 性别
- All
入选标准
- •1.Individuals with androgenic alopecia.
- •2.Healthy adult individuals between18-45 years without any underlying medical conditions that may affect hair regrowth.
- •3.Patient with androgenic alopecia of vertex grade 1-5 of Hamilton Norwood12 or grade 1-2 of Ludwig scale13 without frontal baldness.
- •4.Person who has not taken any medical treatment for androgenic alopecia in any form in last 6 months .
- •5.Willing to give informed consent.
排除标准
- •1.Individuals undergoing concurrent hair loss treatments.
- •2.Pregnant or lactating women.
- •3.Patient with any systemic disease or long-term medication.
- •4.Patients with any local pathology of hair inducing hair fall or undergoing treatment for the same .
- •5.History of hair transplant .
结局指标
主要结局
GFC is better than other blood components in Hair Regrowth
时间窗: 1st, 3rd and 4th months
次要结局
- GFC is better than other blood components in Hair Regrowth(1st, 3rd and 4th months)