跳至主要内容
临床试验/NCT03443102
NCT03443102Unknown不适用

The 15-year Impact of Severe Acute Respiratory Syndrome on Organ Functions, Exercise Capacity, and Quality of Life in Survivors.

Peking University People's Hospital1 个研究点 分布在 1 个国家目标入组 150 人开始时间: 2018年1月25日最近更新:
适应症

试验速览

阶段
不适用
入组人数
150
试验地点
1
主要终点
All-cause disability

研究概览

简要总结

SARS-CoV has caused severe epidemic respiratory disease in human populations. By July 2003, a total of 8,096 probable cases of SARS had been reported including 774 deaths in 27 countries, around one-third of which were health care workers (HCWs). Previous studies have been reported about long-term impacts of SARS infection, including lung function deficiency, steroid-induced osteonecrosis, reduced exercise capacity, and impairment in health-related quality of life (HRQoL). HCWs, especially nurses, have been reported to experience greater psychological distress, particularly increased levels of posttraumatic stress symptomatology (PTSS). But the very complex impacts of this fatal infection on HCWs have not been fully elucidated. It is thus important to follow these occupational patients to detect and manage multi-organ sequelae and functional impairment.

研究设计

研究类型
Observational
观察模型
Case Control
时间视角
Prospective

入排标准

性别
All
接受健康志愿者

入选标准

  • Health care workers who were working at Peking University People's Hospital during the SARS epidemic in 2002-2003

排除标准

  • Refusal to continue the study

结局指标

主要结局

All-cause disability

时间窗: Evaluations would be finished within 90 days after enrollment.

Disabilities arising from physical injuries and/or mental stresses

次要结局

  • Cardiopulmonary function(Evaluations would be finished within 90 days after enrollment.)
  • Life Life quaities mental distress(Evaluations would be finished within 90 days after enrollment.)

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Zhancheng Gao

Head of Respiartory and Critical Care Medicine

Peking University People's Hospital

研究点 (1)

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