The 15-year Impact of Severe Acute Respiratory Syndrome on Organ Functions, Exercise Capacity, and Quality of Life in Survivors.
试验速览
- 阶段
- 不适用
- 入组人数
- 150
- 试验地点
- 1
- 主要终点
- All-cause disability
研究概览
简要总结
SARS-CoV has caused severe epidemic respiratory disease in human populations. By July 2003, a total of 8,096 probable cases of SARS had been reported including 774 deaths in 27 countries, around one-third of which were health care workers (HCWs). Previous studies have been reported about long-term impacts of SARS infection, including lung function deficiency, steroid-induced osteonecrosis, reduced exercise capacity, and impairment in health-related quality of life (HRQoL). HCWs, especially nurses, have been reported to experience greater psychological distress, particularly increased levels of posttraumatic stress symptomatology (PTSS). But the very complex impacts of this fatal infection on HCWs have not been fully elucidated. It is thus important to follow these occupational patients to detect and manage multi-organ sequelae and functional impairment.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Prospective
入排标准
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Health care workers who were working at Peking University People's Hospital during the SARS epidemic in 2002-2003
排除标准
- •Refusal to continue the study
结局指标
主要结局
All-cause disability
时间窗: Evaluations would be finished within 90 days after enrollment.
Disabilities arising from physical injuries and/or mental stresses
次要结局
- Cardiopulmonary function(Evaluations would be finished within 90 days after enrollment.)
- Life Life quaities mental distress(Evaluations would be finished within 90 days after enrollment.)
研究者
Zhancheng Gao
Head of Respiartory and Critical Care Medicine
Peking University People's Hospital
