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The efficacy of Cognitive Behavioural Internet Therapy for adult patients with Chronic Fatigue Syndrome: a randomised controlled trial.

Completed
Conditions
-
Registration Number
NL-OMON25622
Lead Sponsor
Radboud University Nijmegen Medical CentreExpert Centre for Chronic FatiguePostbus 91016500HB Nijmegen
Brief Summary

/A

Detailed Description

Not available

Recruitment & Eligibility

Status
Completed
Sex
Not specified
Target Recruitment
240
Inclusion Criteria

In order to be eligible to participate in this study, patients must meet all of the following criteria:

* >= 18 years;

Exclusion Criteria

Patients who meet any of the following criteria will be excluded from participation in this study:
- Engagement in a legal procedure concerning disability-related financial benefits.

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
The primary outcome measure is fatigue severity assessed with the CIS subscale ‘fatigue severity’.
Secondary Outcome Measures
NameTimeMethod
Secondary outcome measures are: <br>- Level of disabilities assessed with the total score of the Sickness Impact Profile and Short Form 36 Health Survey subscale ‘physical functioning’ ;<br /><br>- Level of psychological distress (total score on Symptom CheckList-90);<br>- Proportion of patients with clinical significant improvement with respect to fatigue severity. Clinical significant improvement is defined as a reliable change index > 1.96 (Jacobson & Truax, 1991) between baseline and T1, and a score of < 35 on the CIS Fatigue Severity subscale at T1;<br>- Quality Adjusted Life Years (Euro Qol Group-6D);<br>- Number of sessions per patient;<br>- Therapist time per patient.
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