The role of antral resection in sleeve gastrectomy. An observational comparative study

Completed

• Conditions: Morbid Obesity, Diabetes Mellitus Type 2; Obesity; Sleeve gastrectomy; Antral resection; Metabolic surgery; Diabetes mellitus type 2

• Registration Number: TCTR20210628001
• Lead Sponsor: niversity of L'Aquila

Brief Summary

A significant difference in %EWL was observed at 3 and 6 months in favor of the 1-DP group (38.9% and 57.8%, respectively) compared to the 6-DP group (31.4% and 49.7%, respectively). No difference in DM2 resolution was observed between two groups during the follow-up period, with similar changes in GLP-1. Significant differences were found between 1-DP and 6-DP group for the reintervention rate and life-threatening complications requiring intensive care unit management .

Detailed Description

Not available

Study Timeline

• Study Completion: 2019-07-31
• Study Start: 2021-06-28
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 109

Inclusion Criteria

BMI > 35 and diabetes mellitus type 2

Exclusion Criteria

Documented psychiatric disorders, alcohol or substance abuse, major diseases such as cancer or autoimmune diseases, corticosteroid therapy, DM2 duration <10 years and HbA1c >6.5%

Study & Design

• Study Type: Observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
weight loss 24 months %EWL ,Effect of extensive antrectomy on glucose metabolism 24 HbA1c level ,Effect of extensive antrectomy on basal plasma GLP-1 levels 24 Basal GLP-1 levels measured using a radioimmunoassay kit

Secondary Outcome Measures

Name	Time	Method
Effect of extensive antrectomy on preoperative mobility an mortality 30 days after procedure Cliven Dindo scale