Development of valid immunoassay methods for Luteinising Hormone (LH) in urine.
Phase 3
- Conditions
- Detection of LH in healthy males, as a sports doping agent.Metabolic and Endocrine - Normal metabolism and endocrine development and function
- Registration Number
- ACTRN12609000300279
- Lead Sponsor
- Sydney South Western Area Health Service (SSWAHS)
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot yet recruiting
- Sex
- Male
- Target Recruitment
- 4
Inclusion Criteria
Healthy males aged 18 to 65.
Not taking any form of androgens.
Exclusion Criteria
History of anabolic steroid use.
Poor health.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method A demonstrated rise in urinary rLH (detected by immunoassay), samples of which will be used to develop valid immunoassay measurements for use in sports anti-doping testing.[All urine passed between 0 and 4 hours, 4 and 8 hours and 8 to 24 hours will be collected as 3 seperate collections.]
- Secondary Outcome Measures
Name Time Method Serum samples for LH and testosterone levels.[All 4 particpants will have blood samples taken prior to commencing the rLH infusion (at 0 minutes) then again at 1,2,3,4,6 and 8 hours. A further blood sample will be taken at 24 hours. All samples will be stored for later analysis.]