A clinical trial to study the effects of two drugs Olmesartan and metoprolol in patients with high blood pressure and heart disease
- Conditions
- Health Condition 1: null- Hypertension with Cardiovascular Disease
- Registration Number
- CTRI/2010/091/001438
- Lead Sponsor
- Glenmark Pharmaceuticals Limited
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 1000
?All CVD patients (prior MI, ACS, PCI, CABG) with hypertension
OR
?All CVD patients (prior MI, ACS, PCI, CABG) with Uncontrolled hypertension (BP > 140/90 mmHg for hypertensive patients and BP > 130/80 mmHg for hypertensive patients with Diabetes or renal disease).
?Not willing to provide written informed consent and comply with the protocol
?Age below 18 years and above 65 years
?Secondary hypertension
?Patients requiring concomitant anti-hypertensive medications other than angiotensin receptor blockers (ARBs) or Metoprolol
?Uncontrolled diabetes mellitus
?Baseline laboratory values outside the clinically acceptable limits
?Pregnant women and lactating mothers
?Females of child bearing age not practicing contraception or not willing to use barrier contraceptive
?Known hypersensitivity to Olmesartan/Metoprolol
?Patients with effort angina more than class II (Drugs like Nitrates, ranolazine or Trimetazidine can be used but not amlodipine or nicorandil).
?Sick sinus syndrome or Atrioventricular block or Heart Failure
Study & Design
- Study Type
- PMS
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method