The Influence Factors of Ovarian Response in Polycystic Ovary Syndrome Patients(PCOS) With In Vitro Fertilization and Embryo Transfer (IVF-ET) Treatment
试验速览
- 阶段
- 不适用
- 入组人数
- 1,000
- 主要终点
- oocyte number
研究概览
简要总结
The purpose of this study is to explore the factors which affect ovarian response of PCOS patients with IVF-ET treatment, in order to provide predictive clinical index for the outcome of IVF-ET treatment in PCOS patients. After figuring out the controllable factors, researchers would be able to educate PCOS patients and improve the success rate while reducing the incidence of complications during the treatment at the same time.
详细描述
Statistics of PCOS patients like age, BMI index and others would be collected. Through distributing questionnaires and query of past cases and collecting data recorded during the ovulation process like monitoring fluctuations in blood and ultrasonic monitoring results, researchers obtain the risk factors of the occurence of Ovarian Hyperstimulation Syndrome(OHSS) in IVF-ET treatment in PCOS patients and set up an OHSS prediction model, choose controllable factors in order to make up guidance and have intervention on patients with PCOS accordingly. The investigators expect this could improve the success rate of IVF-ET treatment in patients with PCOS, provide clues and assist to reduce the risk of the therapy.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Supportive Care
- 盲法
- None
入排标准
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •Clinical diagnosis of PCOS
- •Long schedule time of Luteal phase
- •Available to trace
- •Normal Prolactin level with contraceptive treatment in recent 3 months
排除标准
- •Unwilling to participate
结局指标
主要结局
oocyte number
时间窗: 3 Month
Affect the outcome of IVF-ET treatment
次要结局
- Success Rate(3 Month)
- OHSS complication(3 Month)
研究者
Yilei He
Yilei He
Peking University Third Hospital