Topical Therapy With Cooling Effect in Dry Itchy Skin

Not Applicable

Completed

• Conditions: Compensate the Roughness of the Skin; Compensate the Sensory Symptoms
• Interventions: Device: cooling compound (ph5 Eucerin)

• Registration Number: NCT00669708
• Lead Sponsor: University Hospital Muenster

Brief Summary

Dry skin is a physiological condition and is characterized in contrast to greasy skin by roughness, desquamation and lack of brightness of the skin surface. Subjectively, feelings of tension, burning and itching can occur. The skin reacts more intensive on external and physical noxae. Dry skin is caused by a lack of moisture. This is most common during the winter months, when heating systems dry the air. Bathing with hot water, spending extended periods of time in the hot sun, and the skin's natural aging process also remove moisture and oils from the skin. It is diagnosed through clinical observation. People suffering from dry skin often desire to improve this condition for optical cosmetic reasons and due to the occasional feeling of tension. The aim of this investigation is to observe the improvement (or not) of dry itchy skin by a lotion containing a cooling compound

Detailed Description

The patient use the lotion twice daily for a four-week period. Additionally, the patient receives a documentation sheets to note several parameters. In a sensory assessment, product specific parameter such as spreadability, permeability, lubricating, smell of lotion and cosmetic acceptance during the treatment will be assessed (at the beginning, after 2 weeks, after 4 weeks, 2 weeks after stopping treatment). Before and after skin care measurement, the skin surface will be investigated by d-squames and corneometer. After four weeks the skin care measurement will be terminated and the patient can continue with a treatment of his choice. A monitoring of at least 70 patients is intended.

Study Timeline

• Study Start: 2008-04
• Study First Submitted: 2008-04-22
• Study First Submitted QC: 2008-04-29
• Study First Posted: 2008-04-30
• Status Verified: 2010-02
• Primary Completion: 2010-02
• Study Completion: 2010-02
• Last Update Submitted: 2010-02-01
• Last Update Posted: 2010-02-02

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 70

Inclusion Criteria

1. Patients age: over 18 years
2. itch over VAS 3

Exclusion Criteria

1. pregnancy, lactating women
2. drug abuse
3. active psychosomatic and psychiatric disease
4. active cancer.
5. topical application of tacrolimus, pimecrolimus, corticosteroids or capsaicin two weeks before study start
6. intake of antihistamines, corticosteroids, cyclosporine A and other immunosuppressants, naltrexone, UV-therapy two weeks before study start
7. participation in any other research study during the previous 4 weeks.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
1	cooling compound (ph5 Eucerin)	ph5 Eucerin Lotion with cooling compound
2	cooling compound (ph5 Eucerin)	ph5 Eucerin Lotion

Primary Outcome Measures

Name	Time	Method
Compensate the roughness of the skin Compensate sensory symptoms	4 weeks

Trial Locations

Locations (1)

Department of Dermatology, University of Münster; 🇩🇪 Münster, Germany