Postoperative Cognitive Dysfunction After Total Knee or Hip Replacement Surgery in Fast-track Set-up

Completed

• Conditions: Postoperative Cognitive Dysfunction
• Interventions: Other: no intervention, descriptive study

• Registration Number: NCT01103752
• Lead Sponsor: Lene Krenk

Brief Summary

The aim of this study is to quantify the incidence of postoperative cognitive dysfunction in the elderly patient (\>60y) after total hip or knee replacement surgery. The hypothesis is that the fast-track methodology with a mean hospital stay less than 3 days will help to minimize this reduction in memory and concentration.

Detailed Description

Not available

Study Timeline

• Study Start: 2009-10
• Study First Submitted: 2010-04-13
• Study First Submitted QC: 2010-04-13
• Study First Posted: 2010-04-15
• Primary Completion: 2011-09
• Status Verified: 2011-12
• Study Completion: 2011-12
• Last Update Submitted: 2011-12-13
• Last Update Posted: 2011-12-14

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 225

Inclusion Criteria

• 60 years of age or above
• ASA classification 1-4
• undergoing fast-track hip or knee replacement

Exclusion Criteria

• anaesthesia within the past 90 days
• daily consumption of sleep or anxiety medication
• more than 35 units of alcohol per week
• lack of proper verbal and reading skills, Danish
• Serious hearing or visual impairment
• Mini mental status evaluation (MMSE) < 24
• Parkinsons Disease or other neurological disease causing functional impairment

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Surgery	no intervention, descriptive study	This group (n=220) consist of patients undergoing hip or knee replacement in a fast-track setup and they are tested 3 times for postoperative cognitive dysfunction.

Trial Locations

Locations (1)

The Lundbeck Centre for fast-track hip/knee surgery; 🇩🇰 Copenhagen, Denmark