IRCT20230304057615N1尚未招募Unknown
Comparing the efficacy of hydroalcoholic extract of Iranian oak (germ and seed coat) with proton pump inhibitor (PPI) treatment in improving the symptoms of patients with gastroesophageal reflux
试验速览
- 阶段
- Unknown
- 状态
- 尚未招募
- 入组人数
- 90
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 20 years 至 60 years（—）
- 性别
- All
入选标准
- •Patients who are between 20 and 60 years old
- •Diagnosed with gastroesophageal reflux (GERD) based on clinical symptoms (having reflux at least twice a week), diagnostic endoscopy (esophagogastroduodenoscopy) and the Los Angeles classification (grades A to D)
- •Not taking PPI for at least 1 week before entering the study
排除标准
- •Patients who are infected with H. pylori in the initial diagnostic examinations and before the intervention, based on stomach biopsy or stool test
- •Patients with coagulation disorders or GI bleeding
- •Patients who have a history of upper GI surgery or suffer from other digestive diseases such as irritable bowel syndrome, peptic ulcer, obstructive disease, etc
- •Patients with Zollinger-Ellison syndrome, primary motility disorders, Barrett's esophagus, esophageal stricture, and any severe disease with reflux and malignancy of the upper gastrointestinal tract, as well as pregnant or lactating women
- •Patients who take PPIs from 28 days before diagnostic endoscopy or H2 receptor antagonists from 14 days before diagnostic endoscopy
- •Patients who take NSAIDs or other drugs that may interfere with the interpretation of the study result. (diazepam, quinidine, Dilantin, warfarin, anticholinergics, prostaglandin analogs, or sucralfate)
- •Patients with chronic kidney, lung, and liver diseases and ...
- •Patients who have a history of sensitivity to pantoprazole or seasonal allergies or asthma
- •Patients who consume alcohol or drugs
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