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Fusion rate after using an Intersomatic JULIET®TI cages in lumbar spinal surgery

Phase 4
Completed
Conditions
arthrodesis of the lumbar spine at one level or at two contiguous levels between L2 and S1 to treat:1. Degenerative pathologies (recurrent hernia, degenerative spondylolisthesis, symptomatic disc disease) 2. Spondylolisthesis by isthmic lysis3. Spine deformity (scoliosis, instability)4. Stenosis
Musculoskeletal Diseases
Registration Number
ISRCTN13793886
Lead Sponsor
Spineart (Switzerland)
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Completed
Sex
All
Target Recruitment
52
Inclusion Criteria

1. Skeletally mature patients, aged =80 years
2. Treated by interbody fusion with JULIET-TI at 1 or 2 contiguous levels from L2 to S1
3. Symptomatic degenerative disc disease (SDDD), Recurrent herniated disc, Isthmic spondylolisthesis, or Degenerative spondylolisthesis Grade I
4. Non-smokers or recent quitters (for =3 months)
5. Treated non-surgically (for =6 months)
6. No previous surgery at the level to be treated, or previous surgery at the level to be treated without implantation of any material (i.e. operated for herniated disc or decompression)

Exclusion Criteria

1. Previous surgery at the level to be treated with implantation of material (i.e. arthrodesis or arthroplasty)
2. Infection at the index level
3. Burst fracture and/or comminuted fracture of the vertebral body and/or vertebral plate
4. Osteoporosis, poor bone quality, or tumour
3. Current smokers
4. Spondylolisthesis Grade II or higher
6. Known metal sensitivity
7. Mental illness, hyperactivity
8. Neuromuscular and/or vascular disorder or illness
9. Pregnancy (current or planned next in the next 6 months)

Study & Design

Study Type
Observational
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Interbody fusion status will be qualitatively assessed for all evaluable subjects, using SPECT-CT taken at 6 and 12 months post-surgery
Secondary Outcome Measures
NameTimeMethod
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