The Effects of a Home-based Resistance Training Programme on Body Composition and Muscle Function During Weight Loss in People With Overweight or Obesity: a Randomised Controlled Pilot Trial

University of Glasgow1 site in 1 country48 target enrollmentFebruary 1, 2023

ConditionsOverweight and Obesity

Overview

Phase: Not Applicable
Intervention: Not specified
Conditions: Overweight and Obesity
Sponsor: University of Glasgow
Enrollment: 48
Locations: 1
Primary Endpoint: Change in whole body lean mass
Status: Completed
Last Updated: 2 years ago

Overview Investigators Eligibility Criteria Outcomes Sites Similar Trials

Overview

Brief Summary

The overall aim of this study is to investigate the effects of home-based resistance exercise programme on changes in body composition and strength during weight loss, in people living with obesity or overweight.

Registry

clinicaltrials.gov

Start Date

February 1, 2023

End Date

February 1, 2024

Last Updated

2 years ago

Study Type

Interventional

Study Design

Parallel

Sex

All

Investigators

Sponsor

University of Glasgow

Responsible Party

Principal Investigator

Stuart Gray

Professor

University of Glasgow

Eligibility Criteria

Inclusion Criteria

•Obesity or overweight (BMI ≥ 25kg/m2).
•Passing the Physical Activity Readiness Questionnaire (PAR-q+)

Exclusion Criteria

•Currently take part in more than 1.5 hours of structured exercise per week.
•Having recently (\<6 months) taken part in any resistance exercise training, taking any medications known to affect weight loss.
•Actively engaged in a weight loss programme, having lost more than 2kg weight in the last 6 months.
•Any other reason which would limit ability to perform the exercises and outcome measurements safely.

Outcomes

Primary Outcomes

Change in whole body lean mass

Time Frame: Change from baseline to 12 weeks

whole body lean mass measured via bio-electrical impedance

Secondary Outcomes

Change in body mass(Change from baseline to 12 weeks)
Change in functional physical abilities(Change from baseline to 12 weeks)
Change in whole body fat mass(Change from baseline to 12 weeks)
Change in knee extensor maximal isometric torque(Change from baseline to 12 weeks)
Change in grip strength(Change from baseline to 12 weeks)
Change in vastus lateralis muscle thickness(Change from baseline to 12 weeks)