EXerCise wEight Loss

Not Applicable

Completed

• Conditions: Overweight and Obesity

• Registration Number: NCT05702840
• Lead Sponsor: University of Glasgow

Brief Summary

The overall aim of this study is to investigate the effects of home-based resistance exercise programme on changes in body composition and strength during weight loss, in people living with obesity or overweight.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2023-01-18
• Study First Submitted QC: 2023-01-18
• Study First Posted: 2023-01-27
• Study Start: 2023-02-01
• Status Verified: 2024-02
• Primary Completion: 2024-02-01
• Study Completion: 2024-02-01
• Last Update Submitted: 2024-02-26
• Last Update Posted: 2024-02-28

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 48

Inclusion Criteria

• Obesity or overweight (BMI ≥ 25kg/m2).
• Passing the Physical Activity Readiness Questionnaire (PAR-q+)

Exclusion Criteria

• Currently take part in more than 1.5 hours of structured exercise per week.
• Having recently (<6 months) taken part in any resistance exercise training, taking any medications known to affect weight loss.
• Actively engaged in a weight loss programme, having lost more than 2kg weight in the last 6 months.
• Any other reason which would limit ability to perform the exercises and outcome measurements safely.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Primary Outcome Measures

Name	Time	Method
Change in whole body lean mass	Change from baseline to 12 weeks	whole body lean mass measured via bio-electrical impedance

Secondary Outcome Measures

Name	Time	Method
Change in body mass	Change from baseline to 12 weeks	body mass measured on scales
Change in functional physical abilities	Change from baseline to 12 weeks	A 30-second sit-to-stand test measured functional abilities
Change in whole body fat mass	Change from baseline to 12 weeks	whole body fat mass measured via bio-electrical impedance
Change in knee extensor maximal isometric torque	Change from baseline to 12 weeks	Knee extensor maximal isometric torque measured during a maximal voluntary contraction
Change in grip strength	Change from baseline to 12 weeks	Grip strength measured with a hand held dynamometer
Change in vastus lateralis muscle thickness	Change from baseline to 12 weeks	Muscle thickness of the vastus lateralis muscle measured via ultrasound

Trial Locations

Locations (1)

Stuart Robert Gray; 🇬🇧 Glasgow, United Kingdom