Impact of Elective Versus Emergency Cesarean Delivery on Early Postpartum Depression: a Retrospective Study
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 4,000
- 主要终点
- Edinburgh Postnatal Depression Scale (EPDS) scores, a 10-item self-reported screening tool for postpartum depression (range: 0-30, with higher scores indicating more severe depressive symptoms)
研究概览
简要总结
The goal of this observational retrospective cohort study is to examine the association between mode of delivery and early postpartum depressive symptoms in adult women who delivered at Massachusetts General Hospital. Specifically, the study evaluates whether the urgency of cesarean delivery (elective versus emergency) is associated with differences in Edinburgh Postnatal Depression Scale (EPDS) scores at 6-8 weeks postpartum, compared with elective cesarean delivery and vaginal delivery. The EPDS is a validated 10-item self-report questionnaire with scores ranging from 0 to 30, where higher scores indicate more severe depressive symptoms.
The primary questions are whether EPDS scores differ among women undergoing emergency cesarean delivery, elective cesarean delivery, and vaginal delivery, and whether perioperative and obstetric factors are associated with postpartum depressive symptoms.
This study involves retrospective analysis of de-identified electronic health record data. Participants will not undergo any study-specific interventions.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •Underwent cesarean delivery (elective or emergency) or vaginal delivery during the study period
- •Age 18 years or older
- •Completed at least one Edinburgh Postnatal Depression Scale (EPDS) assessment at 6-8 weeks postpartum
- •Have complete perioperative data available
排除标准
- •Missing 6-8 week postpartum EPDS scores
- •Pregnancy with fetal demise, severe obstetric complications, or atypical maternal conditions
- •History of severe psychiatric disorders (e.g., schizophrenia, bipolar disorder), when identifiable
- •Incomplete perioperative medical records
研究组 & 干预措施
elective cesarean
patients who undergone elective cesarean
urgent cesarean
patients undergone urgent cesarean
vaginal delivery
patients who delivered by vaginal pass
结局指标
主要结局
Edinburgh Postnatal Depression Scale (EPDS) scores, a 10-item self-reported screening tool for postpartum depression (range: 0-30, with higher scores indicating more severe depressive symptoms)
时间窗: 6-8 weeks postpartum
次要结局
- Prevalence of postpartum depression(6-8weeks)
研究者
Jingping Wang, MD, Ph.D.
Associate Professor Staff Anesthesiologist & Pain Physician
Massachusetts General Hospital