A Study of Positive Emotions With Long COVID-19
- Conditions
- Post-Acute COVID-19 Syndrome
- Interventions
- Behavioral: Microdosing of mindfulness
- Registration Number
- NCT05676008
- Lead Sponsor
- University of California, Davis
- Brief Summary
This study is testing a new brief mindfulness practice for people suffering from long COVID-19 symptoms. People suffering from long COVID are particularly vulnerable to negative emotions, as they must also cope with the long-term uncertainty of physical and psychological stress beyond the acute infection. The goal of the study is to measure the ability of a brief mindfulness practice to promote a sense of well-being in people suffering from long COVID.
- Detailed Description
This is a pilot randomized waitlist-controlled clinical trial (RCT) testing a new brief self-care intervention for people suffering from post-acute sequelae SARS-CoV-2 infection (PASC). The overarching goal of this study is to establish the feasibility and early efficacy of microdosing mindfulness as a self-care intervention. The purpose of the intervention is to promote a sense of well-being among PASC patients who currently have limited access to other proven self-care modalities.
Our research question is whether our newly developed training can assist PASC patients to self-microdose mindfulness (5-15 seconds activities in everyday life) and improve on perceived metrics of well-being (primary outcome). Our hypothesis is that self-microdosing mindfulness will evoke positive emotions that can improve well-being on patients suffering of PASC-related symptoms beyond 3 months post COVID-19 infection. If effective, an increased frequency of the mindfulness activity will then help buffer negative emotions (e.g., anger, loneliness, etc.) experienced during the pandemic and associated with ongoing stress and/or somatic symptoms.
Recruitment & Eligibility
- Status
- ACTIVE_NOT_RECRUITING
- Sex
- All
- Target Recruitment
- 400
- Able to participate in online zoom sessions and complete online surveys for 3 months
- English speakers
- Had a mild to moderate in severity COVID-19 infection > 3 months ago, feeling unwell, and are still experiencing in the present at least one PASC-related symptoms:
- Coughing or feeling short of breath
- Loss of smell or change in taste
- Recurrent Fever
- Body aches, headaches, chest pain, or stomach pain
- Brain fog (feeling like you can't think clearly)
- Having trouble sleeping
- Feeling very tired
- Mood changes
- Adults that were admitted to an intensive care unit or placed on a respirator, had invasive heart (heart catheterization) or lung tests (bronchoscopy) performed.
- Prisoners
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description Treatment Microdosing of mindfulness -
- Primary Outcome Measures
Name Time Method Well-being 1 month 14 items from the Mental Health Continuum Short Form
- Secondary Outcome Measures
Name Time Method Depressive symptoms 1, 3 and 12 months Beck Depression Inventory Short Form
Perceived Stress 1, 3 and 12 months Perceived Stress Scale
Physical health 1, 3 and 12 months Physical health symptoms - 11 items + 3 items of COVID symptoms
Anxiety symptoms 1, 3 and 12 months Generalized Anxiety Disorder scale
Well-being 3 and 12 months 14 items from the Mental Health Continuum Short Form
Cardiac symptoms 1, 3 and 12 months Cardiac symptoms by the Kansas City Cardiomyopathy Questionnaire-12 items (KCCQ-12)
Trial Locations
- Locations (1)
University of California Davis
🇺🇸Sacramento, California, United States