Transthoracic Ultrasound in the Diagnosis and Follow-up of Ventilator Associated Pneumonia
试验速览
- 阶段
- 不适用
- 入组人数
- 1
- 主要终点
- detecting ultrasound efficiency in diagnosis and follow up of vap
研究概览
简要总结
To evaluate the sensitivity, specificity and diagnostic accuracy of bedside transthoracic ultrasound examination in the diagnosis and follow up of ventilator associated pneumonia.
详细描述
VAP is the most frequent hospital-acquired infection in intensive care units. Depending on the diagnostic criteria used, its incidence ranges from 5% to 67%. The risk of acquiring VAP is 3% per day during the first 5 days on mechanical ventilation, and it is decreased to 1% per day for the following days.
VAP is suspected when subject shows high grade fever, increase in leukocyte count, change in color of sputum and tachypnea. It's a leading cause of mortality in 15- 65% of the cases.
Serial chest x-ray for diagnosis and follow up, done at time of diagnosis, after 5 days and after 10 days. Chest radiography is consistently carried out after LUS , LUS is done every other day, measuring the largest area of consolidation according to the intercostal space and direction of the probe . Chest radiography is read by two physicians.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Diagnostic
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Mechanical ventilation for at least 48 hours.
- •New or evolving infiltrate on chest radiograph (CXR).
- •Clinical pulmonary infection score more than or equal 6
排除标准
- •Patients who are less than 18 years old.
- •Patients who have evidence of pneumonia before or prior to being mechanically ventilated.
- •Patients with pulmonary infarction.
研究组 & 干预措施
lung ultrasound
using lung ultrasound in diagnosis and follow up of vap measuring the largest area of consolidation according to intercostal space and the direction of the probe
干预措施: transthoracic ultrasound (Device)
结局指标
主要结局
detecting ultrasound efficiency in diagnosis and follow up of vap
时间窗: baseline
Sensitivity, specificity, and diagnostic accuracy of lung ultrasound to diagnose and follow up ventilator-associated pneumonia.
次要结局
- icu stay(baseline)
- hospital stay(basline)
- mortality(basline)
研究者
dina reda ragab gharieb
principal investigator
Assiut University