Clinico-dermoscopic, histopathological and immunological correlation of cutaneous vasculitis in a tertiary care hospital

AIM OF THE STUDY: To study the epidemiology and correlation between clinically diagnosed Cutaneous Vasculitis with its histopathological and direct immunofluorescence findings.

OBJECTIVES OF THE STUDY:

1.     To study the clinical features of cutaneous vasculitis.

2.     To find out the etiology of cutaneous vasculitis

3. To study the correlation between the clinical features, histopathological and direct immunofluorescence findings of cutaneous vasculitis.

METHODOLOGY:

**STUDY SETTING:**Patients coming to the dermatology OPD of teaching hospitals attached to Kasturba Medical College, Mangalore (KMC hospital, Attavar and Government Wenlock hospital).

STUDY DESIGN: It’s a time bound study, cross-sectional and non-interventional study

INCLUSION CRITERIA:

1.     Patients who are willing to give informed written consent for enrollment into the study.

2.     All patient with clinical features suggestive of cutaneous vasculitis

EXCLUSION CRITERIA:

1.     Patient with thrombocytopaenia

2.     Patients with coagulation disorders

3.     Patients on warfarin /heparin

4.     Patients who are not willing to give consent

STUDY DURATION: 18 months

SAMPLING METHOD: Convenience sampling

OUTCOME: Based on clinical, histopathological and DIF findings

DATA COLLECTION TOOL AND ANALYSIS: Patients attending dermatology OPD with clinical features of cutaneous vasculitis will be taken into study. Detailed history will be taken. Detailed cutaneous examination will be performed, and findings will be noted in the proforma. Dermoscopic examination was done using a DermLite-3 (3Gen, San Juan Capistrano, CA) dermoscope.  Consent will be taken from the patient for biopsy after explaining the procedure. Necessary blood investigations will be carried out all the reports will be entered into the proforma and then into excel sheet.

ANALYSIS:

1.Data will be entered in Microsoft Excel and analyzed using Statistical Product and Service Solution (SPSS) version 25.