Study of cutaneous vasculitis

Not yet recruiting

Conditions: Vasculitis limited to the skin, unspecified,

Registration Number: CTRI/2021/03/032398

Lead Sponsor: Indian Association of Dermatologists Venereologists and Leprologists

Brief Summary: **AIM OF THE STUDY**: To study the epidemiology and correlation between clinically diagnosed Cutaneous Vasculitis with its histopathological and direct immunofluorescence findings.

**OBJECTIVES OF THE STUDY**:

1.     To study the clinical features of cutaneous vasculitis.

2.     To find out the etiology of cutaneous vasculitis

3. To study the correlation between the clinical features, histopathological and direct immunofluorescence findings of cutaneous vasculitis.

**METHODOLOGY**:

**STUDY SETTING:**Patients coming to the dermatology OPD of teaching hospitals attached to Kasturba Medical College, Mangalore (KMC hospital, Attavar and Government Wenlock hospital).

**STUDY DESIGN**: Itâ€™s a time bound study, cross-sectional and non-interventional study

**INCLUSION CRITERIA:**

1.     Patients who are willing to give informed written consent for enrollment into the study.

2.     All patient with clinical features suggestive of cutaneous vasculitis

**EXCLUSION CRITERIA:**

1.     Patient with thrombocytopaenia

2.     Patients with coagulation disorders

3.     Patients on warfarin /heparin

4.     Patients who are not willing to give consent

**STUDY DURATION**: 18 months

**SAMPLING METHOD**: Convenience sampling

**OUTCOME**: Based on clinical, histopathological and DIF findings

**DATA COLLECTION TOOL AND ANALYSIS**: Patients attending dermatology OPD with clinical features of cutaneous vasculitis will be taken into study. Detailed history will be taken. Detailed cutaneous examination will be performed, and findings will be noted in the proforma. Dermoscopic examination was done using a DermLite-3 (3Gen, San Juan Capistrano, CA) dermoscope. Consent will be taken from the patient for biopsy after explaining the procedure. Necessary blood investigations will be carried out all the reports will be entered into the proforma and then into excel sheet.

**ANALYSIS:**

1.Data will be entered in Microsoft Excel and analyzed using Statistical Product and Service Solution (SPSS) version 25.

Detailed Description: Not available

Recruitment & Eligibility

Status: Not Yet Recruiting

Sex: All

Target Recruitment: 25

Inclusion Criteria

INCLUSION CRITERIA: 1.
Patients who are willing to give informed written consent for enrollment into the study.
2.All patient with clinical features suggestive of cutaneous vasculitis.

Exclusion Criteria

EXCLUSION CRITERIA: 1.Patient with thrombocytopaenia 2.Patients with coagulation disorders 3.Patients on warfarin /heparin 4.Patients who are not willing to give consent.

Study & Design

Study Type: Observational

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Based on clinical, dermoscopic, histopathological and DIF findings	baseline

Secondary Outcome Measures

Name	Time	Method
Etiology of cutaneous vasculitis	Clinical features of cutaneous vasculitis

Trial Locations

Locations (1): KMC Hospital and Hospitals attached to it
🇮🇳
Kannada, KARNATAKA, India
KMC Hospital and Hospitals attached to it
🇮🇳Kannada, KARNATAKA, India
Dr Pooja R Uppoor
Principal investigator
9481054261
pooja.uppoor@learner.manipal.edu