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Clinical Trials/NCT05508984
NCT05508984
Active, Not Recruiting
N/A

Observational Study of Clinical Outcomes and Patient Satisfaction With Use of the Amma System

Providence Health & Services6 sites in 1 country15 target enrollmentAugust 22, 2022
ConditionsBreast Cancer
InterventionsAmma Cooling Caps

Overview

Phase
N/A
Intervention
Amma Cooling Caps
Conditions
Breast Cancer
Sponsor
Providence Health & Services
Enrollment
15
Locations
6
Primary Endpoint
AMMA Feasibility Within PH&S System
Status
Active, Not Recruiting
Last Updated
8 days ago

Overview

Brief Summary

The primary goal is to conduct a pilot evaluation of the Amma device, to determine whether it is feasible to offer as an option for patients within oncology suites within the PH&S system.

Detailed Description

A novel cold capping device, named Amma™, is now commercially available for use and FDA approved. The Amma system has the potential to be as effective as the Penguin Cold Cap system, but with key innovations that make it more efficient and feasible in the clinic. Innovations include: * Portable and battery powered unit, not requiring dry ice * Form-fitting scalp cap that eliminates the need for frequent cap exchanges The Amma system has not been evaluated for efficacy, and no clinical trials are published. Because of the ease of use and the self-directed administration of the Amma scalp cooling device, we wish to explore this as an option for patients treated within the PH\&S system. To do this, we propose an observational study that evaluates clinical outcomes and patient-reported satisfaction amongst a cohort of patients who undergo self-directed scalp cooling using the Amma system.

Registry
clinicaltrials.gov
Start Date
August 22, 2022
End Date
December 1, 2026
Last Updated
8 days ago
Study Type
Observational
Sex
Female

Investigators

Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • \- Women with stage I-III breast cancer are eligible to participate if:
  • They consent to conduct baseline (week 0) and follow-up (week 4 post-chemo) surveys/interviews
  • They consent to be photographed at baseline (week 0) and follow-up (week 4 post-chemo), to document hair retention outcomes
  • Curative-intent chemotherapy is planned with a taxane-based, anthracycline-sparing chemotherapy regimen (which includes but may not be limited to: TC x 4, T x 12, TCHP x6)

Exclusion Criteria

  • Not provided

Arms & Interventions

Single Arm

Anywhere from 14 to 0 days prior to treatment, enrolled subjects will complete the following questionnaires, and their hair will be photographed by research staff. Once enrolled, subjects will be provided the Amma device by the clinic on days of chemotherapy treatment, and upon completion of treatment it will be returned to the clinic for safekeeping. Upon completion of chemotherapy, anywhere from 3-6 weeks following treatment, subjects will repeat the questionnaires and their hair will be photographed again. Subjects will then complete their enrollment in the study.

Intervention: Amma Cooling Caps

Outcomes

Primary Outcomes

AMMA Feasibility Within PH&S System

Time Frame: End of Treatment (4 to 8 months, depending on duration of their chemotherapy regimen)

The primary goal is to conduct a pilot evaluation of the Amma device, to determine whether it is feasible to offer as an option for patients with early-stage breast cancer within oncology suites within the PH\&S system. Patient satisfaction will be assessed using pre and post treatment questionnaires related to the Amma system and an exit interview.

Secondary Outcomes

  • Patient Satisfaction Utilizing the Was It Worth It Questionnaire(End of Treatment (4 to 8 months, depending on duration of their chemotherapy regimen))
  • Patient Reported Outcome Utilizing Dean's Score(End of Treatment (4 to 8 months, depending on duration of their chemotherapy regimen))
  • Patient Reported Outcome Utilizing Body Image Scale(End of Treatment (4 to 8 months, depending on duration of their chemotherapy regimen))

Study Sites (6)

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