Mental imagery (pictures in the mind's eye) psychological talking therapy for psychosis - 2

Not Applicable

• Conditions: Schizophrenia, schizotypal and delusional disorders; Mental and Behavioural Disorders

• Registration Number: ISRCTN81150786
• Lead Sponsor: Pennine Care NHS Foundation Trust

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2022-06-14
• Last Update Posted: 18 June 2024
• Study Completion: 2024-06-30

Recruitment & Eligibility

• Status: Ongoing
• Sex: All
• Target Recruitment: 45

Inclusion Criteria

1. Meeting criteria for a schizophrenia-spectrum diagnosis (ICD-10 codes F20, F22, F23, F25, F28, F29; ICD-11 codes F20, F22, F23, F25, F28, F29; ICD-11 codes 6A20, 6A21, 6A23, 6A24, 6A2Y,6A2Z) AND Score of 3 Mild or above on P1 Delusions or P3 Hallucinations on Positive and Negative Syndrome Scales (PANSS), OR
a criterion level of positive symptoms severity indicated by a score of > 3 (mild symptom present) on the delusions (P1), hallucinations (P3), grandiosity (P5) or suspiciousness (P6) items of the PANSS in the previous week (this is usually the operational criteria to under the care of early intervention psychosis team) And/or the psychosis transition criteria of the CAARMS
2. Aged 18 years and above
3. Identifying a distressing image (Rated 50% distressing or above) related to the psychotic experience scoring 3 or above on PANSS. The participant will self-report the image as distressing (e.g., Have you had a distressing image over the past month? Yes/No What would you rate the distress over the past month from 0-100?).
4. Capacity to give informed consent,
5. Under the care of an NHS mental health team the study is recruiting from
6. With a keyworker/access to a duty team worker.

Qualitative study:
1. Capacity to provide informed consent for interviews
2. Consent to have interviews recorded
3. Participation in iMAPS-2, with at least 4 weeks involvement in iMAPS-2 post randomisation
4. Sufficient English language proficiency to take part in qualitative interviews or agreement to the use of an interpreter

Clinician referrers qualitative Study:
1. Consent to have interviews digitally recorded
2. Experience of referring at least one service user to the iMAPS-2 Study

Exclusion Criteria

1. Primary diagnosis of alcohol, substance misuse disorder, or bipolar disorder (affective psychosis)
2. Secondary presenting difficulties such as severe addiction, acute suicidal risk, dementia, neurological disorder.
3. Developmental disability (moderate to severe learning difficulty)
4. Acquired brain injury/organic syndrome
5. Currently participating in physical or mental health treatment studies or receiving psychological therapy
6. Unable to complete the measures in written English (due to assessment battery psychometric validation in English)
7. In forensic settings
8. Unmanageable level of risk of violence to researchers or clinicians (harassment behaviour – stalking).

Study & Design

• Study Type: Interventional
• Study Design: Not specified