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临床试验/NCT03417609
NCT03417609已完成不适用

Interest of a Tongue Strength Measurement in the Screening for Sarcopenia in Hospitalized Elderly Patients

Murielle Surquin1 个研究点 分布在 1 个国家目标入组 110 人开始时间: 2018年2月7日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
110
试验地点
1
主要终点
Tongue strength

研究概览

简要总结

Sarcopenia is a syndrome characterized by a progressive and generalized loss of skeletal muscle mass, strength and function that increases the risk of physical dependence, impaired quality of life and mortality. This is a major public health problem. Indeed, its prevalence has been estimated at 63.8% for elderly patients hospitalized in acute geriatric unit.

Several methods of sarcopenia screening exist at present. The European Working Group on Sarcopenia in Older People (EWGSOP) proposes to carry out three examinations for the diagnosis of sarcopenia: the Dual-Energy X-ray Absorptiometry (DEXA) test and two motor tests (walking speed and hand test). These measurements have already been evaluated and validated. They are reliable, inexpensive and easily achievable in clinical routine.

Recent studies have shown that decreased muscle mass and / or strength could be associated with dysphagia. Indeed, many muscles of the head and neck are simultaneously solicited for swallowing coordination. This suggests that a reduction in the mass or strength of these muscles could impact the swallowing function. The investigator's hypothesize that loss of lingual muscle strength may be associated with sarcopenia. The study will measure the tongue strength using the Iowa Oral Performance Instrument (IOPI) in a geriatric population with or without sarcopenia.

  • Determine the incidence of lingual hypotonia in hospitalized elderly sarcopenia patients.
  • To compare the sensitivity, the specificity of the measurement of the force of the tongue with the usual measures proposed by the EWGSOP in the context of screening for sarcopenia.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Prospective

入排标准

年龄范围
65 Years 至 —(Older Adult)
性别
All
接受健康志愿者

入选标准

  • Patients hospitalized in an acute geriatric unit within the CHU Brugmann.

排除标准

  • 未提供

结局指标

主要结局

Tongue strength

时间窗: 6 months

The Iowa Oral Performance Instrument is a validated device for assessing the strength of the tongue. This involves placing the tip of a tube in the mouth and asking the patient to exert pressure on it. Thus, a pressure measurement expressed in kPa makes it possible to objectify the tongue strength.

次要结局

  • Albumin concentration(6 months)
  • Skeletal Mass Muscle Index(6 months)
  • Pre-Albumin concentration(6 months)
  • Hand grip strength(6 months)
  • Minimal nutritional assessment (MNA-SF) score(6 months)
  • Mini Mental State Examination (MMSE) score(6 months)
  • Walking speed(6 months)

研究者

申办方类型
Other
责任方
Sponsor Investigator
主要研究者

Murielle Surquin

Head of clinic

Brugmann University Hospital

研究点 (1)

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