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Thrombolysis With Intra-arterial Urokinase

Completed
Conditions
Arterial Occlusion Mesenteric Artery Superior
Interventions
Procedure: intra-arterial urokinase thrombolysis
Registration Number
NCT04688879
Lead Sponsor
Chang Gung Memorial Hospital
Brief Summary

Patients with acute superior mesenteric artery (SMA) occlusion were included in this study. The clinical presentation and effect of the recanalization of the SMA was analyzed on follow-up angiography.

Detailed Description

Thirteen patients with acute SMA occlusion who underwent intra-arterial urokinase thrombolysis between 2008 and 2020 were retrospectively evaluated.

Clinically, the abdominal pain and the effect of the SMA on angiography will be compared in response and non-response groups.

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
13
Inclusion Criteria
  • Clinical diagnosis of SMA occlusion
Exclusion Criteria
  • shock in the triage screening
  • peritonitis
    1. intramural gas, mesenteric or portal venous gas on contrast-enhanced abdominal CT

Study & Design

Study Type
OBSERVATIONAL
Study Design
Not specified
Arm && Interventions
GroupInterventionDescription
According to the degree of occlusion, 13 patients were divided into complete and incomplete groups.intra-arterial urokinase thrombolysisSeven patients were complete occlusion and 6 patients were incomplete occlusion and all underwent thrombolysis with intra-arterial urokinase and the outcome was analysed..
Primary Outcome Measures
NameTimeMethod
Thrombolysis with intra-arterial urokinase for acute superior mesenteric artery occlusion: Outcome analysisDaily series follow-up angiography in the next 72 hours after thrombolysis with intra-arterial urokinase.

Degree of patency and appearance of the SMA will be analyzed in the follow-up angiography.

Secondary Outcome Measures
NameTimeMethod

Trial Locations

Locations (1)

Chang Gung memorial Hospital

🇨🇳

TaoYuan City, Taiwan

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