A randomized comparative clinical trial to evaluate the efficacy of madhughrita pratisaran with calcium dobesilate in raktarsha
试验速览
- 阶段
- 1/2 期
- 状态
- 尚未招募
- 发起方
- 入组人数
- 60
- 试验地点
- 1
- 主要终点
- To compare efficacy of Madhughrita Pratisaran and Calcium dobesilate applied locally thrice a day for 7 days in the management of Raktarsha.
研究概览
简要总结
Oneof the most common ano-rectal conditions is Hemorrhoids. Cause may be inrelation to the food or the faulty life style. In common language it isreferred as Piles. The prevalence rate of piles is 4.4% in the world that isabout 10 million people.The diseases that is troubling the human beingsince the time immemorial is the Arsha because of its manifestation at the GudaPradesh which is the “ Moola of Shariraâ€.Haemorrhoids, also called piles, are vascularstructures in the anal canal. They become a disease when swollen or inflamed.The signs and symptoms of haemorrhoids depend on the type present. Internalhaemorrhoids are usually present with painless, bright red rectal bleeding whendefecating. External haemorrhoids often results in pain and swelling in area ofthe anus.
Drugs taken for study:
1. Madhu
| Guna |
Madhur Kashayanuras , Ruksha, Shita, Laghu, Pishcchil, Yogvahi mrudu
|Karma
Lekhan, Shodhan, Ropan, Agnidipan
|Doshaghnatwa
Tridosha prashaman
|Vikar nashakatva
Arsha,Kushtha, Meha, Badhdamalata
|Dhatugamitva
Meda, Majja, Medhaprasadaka,
2. Ghrita
| Guna |
Madhur, Sheet, Madhurvipaki
| Karma
Dahaprashaman, swara varnya prasadanm,
Rajoroadh
| Doshanghanta
Vataprashaman, pitta prashamana shodhan
| vikarnashtva
Visarp, unmad, shotha, kashtha atarava,
3. Calcium dobesilate-
it is combination of calcium dobisilate 0.25%+ hydrocortisone 0.25%+lignocaine 3%+ zinc oxide 5%
It is a used for local application it islocal anesthetic, anti inflammatory and venous decongestant and improves vinoustone
In my study I am going to study and compare effect of Madhughrita Pratisaran with Calcium dobesilate in management of Bleeding Piles.
研究设计
- 研究类型
- Interventional
- 分配方式
- Coin toss, Lottery, toss of dice, shuffling cards etc
- 盲法
- Open Label
入排标准
- 年龄范围
- 20.00 Year(s) 至 50.00 Year(s)（—）
- 性别
- All
入选标准
- •1 Age between 20-50 yrs 2 Both male and female and others 3 patients with 1st 2nd, 3rd degree haemorrhoids 4 bleeding piles.
排除标准
- •1 Prolapsed of the rectum 2 k/c/o Fistula in ano 3 perineal Abscess 4 k/c/o Malignancy 5 K/C/O Crohns disease 6 K/C/O Ulcerative colitis 7 Rectal polyp 8 K/C/O Diverticulitis 9 K/C/O Hypertension 10 Bleeding Disorders 11 Hb % less than 7 gm%.
结局指标
主要结局
To compare efficacy of Madhughrita Pratisaran and Calcium dobesilate applied locally thrice a day for 7 days in the management of Raktarsha.
时间窗: 7 days with follow up on 3rd, 5th and 7th day
次要结局
- To study the adverse effect of Madhughrita Pratisaran if any(7 days with follow up on 3rd, 5th and 7th day)