Tear Osmolarity Over Time With Artificial Tears
- Conditions
- Dry Eye
- Interventions
- Drug: Artificial tears
- Registration Number
- NCT01227226
- Lead Sponsor
- Hom, Milton M., OD, FAAO
- Brief Summary
The effect of artificial tears on tear osmolarity
- Detailed Description
Tear osmolarity measures the amount of solutes in the human tear film. The higher the reading, the more likely the patient has dry eyes. Some say it has "potential to be the gold standard" of dry eye testing. The investigators study the tear osmolarity at different time points after instillation of artificial tears.
Recruitment & Eligibility
- Status
- UNKNOWN
- Sex
- All
- Target Recruitment
- 48
Between the ages of 18 and over inclusive. Males or females Any race or ethnic background Patient is in generally good & stable overall health. Patient likely to comply with study guidelines & study visits. Informed consent signed. Subjective evaluation of symptom of dryness (SESoD): Score 2 (Mild)
Corneal refractive surgery within 6 months of this study. Intra-ocular surgery within 6 months or ocular laser surgery within 6 months. Pregnant or lactating women. Ocular pathology (includes glaucoma and cataract), which could impact results and/or place patient at risk.
Corneal staining Grade 3 or higher No Restasis for past 3 months Discontinue topical medications for at least 1 week
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description Refresh tears Artificial tears Allergan's Refresh tears artificial tear Systane Ultra Artificial tears Alcon's Systane Ultra artificial tear Visine Artificial tears Visine artificial tear Blink tears Artificial tears AMO's blink tears artificial tear
- Primary Outcome Measures
Name Time Method Tear osmolarity 2 days Tear osmolarity measured with TearLab instrument
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Milton M. Hom, OD, FAAO.
🇺🇸Azusa, California, United States