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The IMPROV Project: Improving Mental Health and Substance Use Treatment Provision (IMPROV) Among People Living With HIV (Human Immunodeficiency Virus) in Atlanta

Not Applicable
Conditions
Mental Health Disorder
Substance Use Disorder
Implementation Science
Stigmatization
Interventions
Behavioral: Modified Health Policy Project (HPP) HIV-Stigma and Discrimination Reduction Training Curriculum
Device: You℞ Decision prescribing platform
Registration Number
NCT05415891
Lead Sponsor
RTI International
Brief Summary

This project consists of a pilot trial to assess the preliminary impact of a stigma-reduction training to reduce clinic-level stigma and the You℞ Decision prescribing platform to increase HIV care providers' self-efficacy related to prescribing psychiatric medication for depression, post-traumatic stress disorder (PTSD), and bipolar disorder as well as naltrexone for alcohol use disorder (AUD).

Detailed Description

The study will pilot test a two-level strategy to improve integration of pharmacotherapy for serious mental health and alcohol use disorders among people living with HIV (PLHIV) in Ryan White-funded healthcare centers in Atlanta, Georgia. A small pilot trial will be conducted in the two clinic study sites to assess the acceptability, feasibility, adoption, and preliminary impact of a stigma-reduction training and the You℞ Decision prescribing platform.

The researchers will fulfill the purpose of this study through the following aims:

Aim 1: To conduct formative activities with PLHIV, HIV care providers, and our Community Collaborative Board (CCB) to adapt a stigma-reduction training to address mental health and substance abuse-related stigma among clinic staff and engage HIV care providers and an expert panel to develop the You℞ Decision prescribing platform to support HIV care providers to offer pharmacotherapy to treat depression, PTSD, bipolar disorder, and AUD (completed).

Aim 2: To assess the acceptability of the stigma-reduction training among clinic staff and the feasibility, acceptability, and adoption of the You℞ Decision prescribing platform during clinical encounters among providers in HIV care settings.

Aim 3: To use idiographic methods to conduct a pilot trial to assess the preliminary impact of the stigma-reduction training on clinic-level stigma and of the You℞ Decision prescribing platform on HIV care providers' self-efficacy to prescribe psychiatric medications and naltrexone as well as the impact of the stigma-reduction training and platform to increase the percentage of eligible patients who receive and accept prescriptions to treat depression, PTSD, bipolar disorder, and AUD.

This implementation science study aims to reduce HIV-associated comorbidities by improving the integration of mental health and AUD treatment into Ryan White-funded care sites. If the findings indicate that the stigma-reduction training and prescribing platform are feasible, this study will be the impetus for the scale up these strategies to additional Ryan White-funded care sites in Georgia.

Recruitment & Eligibility

Status
UNKNOWN
Sex
All
Target Recruitment
333
Inclusion Criteria

Stigma Reduction Training

  • be 18 years of age or older
  • be a staff member at the clinic study site randomized for the stigma-reduction training

Clinic Staff Survey

  • work at one of the two clinic study sites
  • be 18 years of age or older

Patient Survey

  • 18 or older
  • report being HIV positive
  • have received care from a clinic study site recently

Pilot Trial

  • provide HIV care
  • be 18 years of age or older
  • be licensed to provide prescription medication
  • provide care at one of the two clinic study sites
Exclusion Criteria

Stigma Reduction Training

  • Have been part of the formative activities

Clinic Staff Survey

  • Have been part of the formative activities.

Patient Survey

  • HIV negative
  • Have not attended a study clinic site recently
  • Have participated in the formative activities

Pilot Trial

  • Not a prescribing provider
  • Not a provider at a study clinic site recently
  • Have been part of the formative activities

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
Stigma-Reduction Training Arm + YouRx Prescribing PlatformYou℞ Decision prescribing platformStaff working in the clinic in this arm will be offered a whole-site stigma reduction training. Participating HIV care providers will have access to the YouRx Prescribing Platform.
YouRx Prescribing Platform OnlyYou℞ Decision prescribing platformStaff working in the clinic in this arm will not be offered a whole-site stigma reduction training. However, staff will be offered this training at the conclusion of the study. Participating HIV care providers will have access to the YouRx Prescribing Platform.
Stigma-Reduction Training Arm + YouRx Prescribing PlatformModified Health Policy Project (HPP) HIV-Stigma and Discrimination Reduction Training CurriculumStaff working in the clinic in this arm will be offered a whole-site stigma reduction training. Participating HIV care providers will have access to the YouRx Prescribing Platform.
Primary Outcome Measures
NameTimeMethod
Provider-Level Outcome: Acceptability of the YouRx Decision Prescribing Platform3 months follow-up

4-item measure to assess provider satisfaction with the You℞ Decision platform

Clinic Staff-Level Outcome: Observed Stigma Reduction3 months follow-up

Clinic staff observed stigmatizing behaviors toward those with serious mental health and/or substance use disorders

Provider-Level Outcome: Adoption of the YouRx Decision Prescribing PlatformWeekly (12 weeks)

Provider use of the You℞ Decision prescribing platform

Provider-Level Outcome: Feasibility of the YouRx Decision Prescribing Platform3 months follow-up

4-item measure to assess provider perception that the You℞ Decision platform can be integrated into usual care

Provider-Level Outcome: Provider Self-Efficacy3 months follow-up

11-item survey to assess providers confidence to treat serious mental health disorders and AUD

Clinic-Level Outcome: Adoption of Psychiatric Medication and Naltrexone3 months follow-up

Percentage of eligible patients who receive a prescription for psychiatric medication or naltrexone or an in-house referral for psychiatric treatment from their HIV care provider.

Clinic Staff-Level Outcome: Acceptability of Stigma Reduction TrainingImmediately post-training

4-item self-report measure to assess clinic staff's satisfaction with the stigma reduction training

Health Consumer-Level Outcome: Observed Stigma Reduction3 months follow-up

Experienced or observed stigma and discrimination from clinic staff based on serious mental health or substance use disorder

Provider-Level Outcome: Usability of the YouRx Decision Prescribing Platform3 months follow-up

21-item survey to assess the ease of use of the You℞ Decision prescribing platform

Clinic-Level Outcome: Reach of Prescription of Psychiatric Medication and Naltrexone3 months follow-up

Percentage of eligible patients who fulfill a prescription for a psychiatric medication or naltrexone or in-house referrals at the clinic level

Percentage of eligible patients who fill a prescription for psychiatric medication or naltrexone or attend an intake appointment with an in-house mental health or substance use provider.

Secondary Outcome Measures
NameTimeMethod

Trial Locations

Locations (2)

Positive Impact Health Center--Decatur Location

🇺🇸

Decatur, Georgia, United States

Positive Impact Health Center--Duluth Location

🇺🇸

Duluth, Georgia, United States

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