Multi- Institutional study to re-define the factors determining oral cavity cancer treated with surgery and adjuvant radiotherapy or chemoradiotherapy
Not Applicable
- Conditions
- Health Condition 1: C148- Malignant neoplasm of overlappingsites of lip, oral cavity and pharynxHealth Condition 2: C00-C14- Malignant neoplasms of lip, oral cavity and pharynxHealth Condition 3: null- Non-metastatic patients at diagnosis (Stage I-IVB per AJCC 7th edition staging) treated for squamous cell carcinoma of the oral cavity between 1/1/2005 and 1/1/2015
- Registration Number
- CTRI/2019/07/020269
- Lead Sponsor
- A
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
1.Patients treated at participating institutions for squamous cell carcinoma of the oral cavity treated with primary surgical resection
2.Patients will have undergone primary surgical resection between 1/1/2005 and 1/1/2015
3.Patients will be staged Stage I-IVB per AJCC 7th edition staging.
4.Patients will be age 18 years or older at time of initial surgery.
Exclusion Criteria
1. History of prior radiotherapy to the head and neck
2. Non-squamous histologies of the head and neck will be excluded.
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method This large international collaboration could help generate hypothesis and maybe enable subsequent studies to answer questions that can be asked of a large oral cavity database which could include: <br/ ><br>1) Predictors of failure in early stage disease treated with surgery monotherapy <br/ ><br>2) Role of chemotherapy in intermediate risk resected disease <br/ ><br>3) Risk of contralateral failure in tongue cancer patients <br/ ><br>4) Quality surgical metrics and its impact on outcomes <br/ ><br>Timepoint: At single time point after enrolment <br/ ><br>
- Secondary Outcome Measures
Name Time Method ATimepoint: NA