NCT01821820已完成不适用
Influence of Pistachios on Performance and Exercise-induced Inflammation, Oxidative Stress, and Immune Dysfunction in Athletes: a Metabolomics-based Approach.
适应症
干预措施
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 40
- 试验地点
- 1
- 主要终点
- Shifts in metabolites (metabolomics)
研究概览
简要总结
Ingestion of 3 ounces of pistachio nuts per day for two weeks before and the day of cycling intensely for 75 kilometers will support substrate utilization during exercise (as determined through metabolomics) and improve performance compared to water only, and attenuate inflammation, oxidative stress, and immune dysfunction during 24 hours of recovery.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Prevention
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 55 Years（Adult）
- 性别
- Male
- 接受健康志愿者
- 是
入选标准
- •Male endurance cyclists
- •Capable of exercising for 2.5 h at a high intensity in the lab
- •Ages 18-55
- •Agree to train normally and stay weight stable.
- •Agree to avoid the use of large dose vitamin/mineral supplements
- •Agree to avoid herbs and medications that influence inflammation
排除标准
- •Regularly take supplements or medicines known to effect inflammation.
- •At moderate or high risk for cardiovascular disease.
- •Younger than 18 or older than 55 years of age.
- •No history of competing in cycling races.
研究组 & 干预措施
Pistachios
Experimental
Pistachio treatment (3 oz/d) for two weeks; 3 oz pistachio nuts and water (1.5 oz. before, and 1.5 oz during) cycling 75 km.
干预措施: Pistachios (Other)
No pistachios
No Intervention
No pistachios for two weeks, or before and during 75 km cycling.
结局指标
主要结局
Shifts in metabolites (metabolomics)
时间窗: 14-day period
Shifts in metabolites pre-and post-14-days supplementation, and then after 75-km cycling, and the next morning.
次要结局
- Immune Function(14-day period)
- Inflammation(14-day period)
- Oxidative Stress(14-day period)
研究者
研究点 (1)
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