Relationship of Skeletal Muscle Thickness, Strength, and Diaphragm Function in Adults With CF

Completed

• Conditions: Cystic Fibrosis

• Registration Number: NCT04892485
• Lead Sponsor: Marmara University

Brief Summary

31 CF patients and 23 healthy sex and age-matched volunteers were enrolled. All subjects underwent pulmonary function tests, 6-minute walking tests. Body Mass Index and Fat Free Mass Index were measured via a body composition analyser. Diaphragm ultrasonography (to measure thickening fraction), quadriceps femoris muscle ultrasonography were performed. A dynamometer was used to measure each subjects handgrip strength.

Detailed Description

Not available

Study Timeline

• Study Start: 2017-09-01
• Primary Completion: 2018-04-30
• Study Completion: 2018-04-30
• Status Verified: 2021-05
• Study First Submitted: 2021-05-14
• Study First Submitted QC: 2021-05-14
• Last Update Submitted: 2021-05-14
• Study First Posted: 2021-05-19
• Last Update Posted: 2021-05-19

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 31

Inclusion Criteria

• CF diagnosed
• Age 18 and above

Exclusion Criteria

• Having a pulmonary flare up within the previous month
• Pregnancy

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Muscle Thickness, Strength and Diaphragm Thickening Fraction of CF Patients	2 months	Measured via USG and handheld dynamometer

Trial Locations

Locations (1)

Marmara University School of Medicine; 🇹🇷 Istanbul, Turkey