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A Year Long Study to Evaluate the Safety of the Combination of Valsartan (320 mg) and Amlodipine (5 mg) in Patients With Hypertension

Phase 3
Completed
Conditions
HYPERTENSION
Registration Number
NCT00170976
Lead Sponsor
Novartis
Brief Summary

A ONE YEAR SAFETY STUDY FOR PATIENTS WHO COMPLETE STUDY VAA489A2307.

Detailed Description

Not available

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
403
Inclusion Criteria
  • SUCCESSFUL COMPLETION OF VAA489A2307 CORE TRIAL
  • VISIT 7 BLOOD PRESSURE MUST BE MSDBP ≤ 95 mmHg AND MSSBP ≤ 150 mmHg
Exclusion Criteria
  • PATIENTS WHO EXPERIENCED ANY ADVERSE EVENTS CONSIDERED SERIOUS AND DRUG RELATED IN VAA489A2307 CORE

Other protocol-defined exclusion criteria may apply.

Study & Design

Study Type
INTERVENTIONAL
Study Design
SINGLE_GROUP
Primary Outcome Measures
NameTimeMethod
Adverse events and serious adverse events at each study visit for 6 or 12 months
Secondary Outcome Measures
NameTimeMethod
Hematology and blood chemistry after 6 or 12 months
Change from baseline in diastolic blood pressure from baseline after 6 or 12 months
Change from baseline in systolic blood pressure from baseline after 6 or 12 months
Change from baseline in standing diastolic and systolic blood pressure after 6 or 12 months
Change from baseline in sitting and standing pulse after 6 or 12 months

Trial Locations

Locations (2)

Sites in germany

🇩🇪

Multiple Locations, Germany

Novartis Pharmaceuticals

🇨🇭

Basel, Switzerland

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