Analyses of Bone Age Determined by Ultrasound in a Cohort of Brazilian Control Children and Adolescents: Comparison With Conventional Bone Age Determined by X-Ray
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Control, Population
- Sponsor
- Faculdade de Ciências Médicas da Santa Casa de São Paulo
- Enrollment
- 500
- Locations
- 1
- Primary Endpoint
- bone age determination by ultrasound (BAUS)
- Last Updated
- 8 years ago
Overview
Brief Summary
Aiming to validate the use of bone age determined by ultrasound (BAUS) in Brazilian children, normal control students will be studied. X-Ray bone age (RXBA) and BAUS will be determined in 500 children and adolescents of both genders, with chronological age varying from 6-16 years.
Concordance analysis and the correlation between both BA determination methods will be performed.
Detailed Description
Bone age is a valuable method to recognize the maturation status of development and growth. Classical analyses is performed by using the Greulich and Pyle X-Ray measurement. Such analyses have some restrictions such as intra- and inter observer variability, and variable synchronicity of bone maturation. Bone age determined by ultrasound (BAUS) has been indicated as a fast and reproducible method, allowing decimal BA determination and avoiding the need for X-Ray. Our aim is to validate the BAUS method in Brazilian normal controls. School students of both genders, with age varying from 6 to 16 years will be included.
Investigators
Carlos Alberto Longui
Full Professor
Faculdade de Ciências Médicas da Santa Casa de São Paulo
Eligibility Criteria
Inclusion Criteria
- •absence of chronic illness and drug ingestion
Exclusion Criteria
- •any chronic disease or medicine use
- •body mass index: \< -2SDS or \> +2SDS
- •stature : \< -2SDS or \> +2SDS
Outcomes
Primary Outcomes
bone age determination by ultrasound (BAUS)
Time Frame: chronological ages between 6 and 16 years of age
Determination of bone age in years by employing a ultrasound device