GON-injection for a sooner and better treatment of cluster headache: a double-blind randomized controlled trial

Phase 3

Completed

• Conditions: Hoofdpijn; Cluster headache; Horton's neuralgia

• Registration Number: NL-OMON48495
• Lead Sponsor: eids Universitair Medisch Centrum

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 15 April 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 80

Inclusion Criteria

- Patients have to be diagnosed with episodic cluster headache according to the
international classification of headache disorders - third edition, ICHD-3
- Patients have to be aged 18 years or older
- Patients need to be newly diagnosed and treatment naïve, or already diagnosed
and currently free from prophylactic treatment
- Patients need to have a mean of 1 or more attacks per day in the 3 days
preceding inclusion.
- Patients should be in their cluster period for shorter than 4 weeks before
inclusion.

Exclusion Criteria

- A contraindication for treatment with steroids or verapamil
- The use of anticoagulants or known bleeding disorder.
- Use of any prophylactic medication for cluster headache
- Patients with a history of other primary headache who are currently using
prophylactic medication for this headache
- Pregnancy

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>The primary endpoint of this study is total dose of verapamil used during the<br /><br>study period </p><br>