Robotic -Assisted Rehabilitation for Multiple Sclerosis: An Adaptive Approach for Individualized Therapy
Trial Snapshot
- Phase
- Not Applicable
- Status
- Completed
- Sponsor
- Enrollment
- 9
- Locations
- 1
- Primary Endpoint
- Maximum isometric wrist force
Study Overview
Brief Summary
Therefore, the purpose of this study was to evaluate four-weeks of an upper limb robotic intervention for persons with Multiple Sclerosis. Participants completed a resistive and adaptive robotic training intervention whereby participants trained three times weekly for four consecutive weeks.
Detailed Description
Nine individuals with Multiple Sclerosis participated and were placed into two groups based that either trained their self-reported less affected limb (indirect training group; N=4) or trained their self-reported more affected limb (direct training group; N=5).
Study Design
- Study Type
- Interventional
- Allocation
- Randomized
- Intervention Model
- Parallel
- Primary Purpose
- Treatment
- Masking
- None
Eligibility Criteria
- Ages
- 18 Years to 75 Years (Adult, Older Adult)
- Sex
- All
- Accepts Healthy Volunteers
- No
Inclusion Criteria
- •Diagnosis of MS
- •No other neurological diagnosis
- •No injury to the upper limb (i.e., broken bones)
Exclusion Criteria
- •Relapse in the past 6 months
Arms & Interventions
Indirect training group
trained their self-reported less affected upper limb
Intervention: end-effector robotic training (Device)
Direct training group
trained their self-reported most affected limb
Intervention: end-effector robotic training (Device)
Outcomes
Primary Outcomes
Maximum isometric wrist force
Time Frame: Baseline (Week 0) and immediately post intervention (Week 4)
the participant's arm was fully extended and rested on the table, and participants were instructed to exert force at the wrist joint (F/E, RD/UD) as hard as they could against the stationary load cell that rested on the metacarpophalangeal joints (Model: BG 500, Mark-10 Corporation, New York, USA). Two maximal exertions were completed and the largest value was recorded.
maximum grip force
Time Frame: Baseline (Week 0) and immediately post intervention (Week 4)
Participants were asked to complete one trial of a maximum grip test (Baseline Evaluation Instruments). Held with a straight arm, 45° abduction by the side and hand/wrist neutral, participants were asked to squeeze the handle as hard as possible for 3 seconds and grip force (Newton) was recorded.
Maximum isometric wrist force
Time Frame: Baseline (Week 0) and immediately post intervention (Week 4)
the participant's arm was fully extended and rested on the table, and participants were instructed to exert force at the wrist joint (F/E, RD/UD) as hard as they could against the stationary load cell that rested on the metacarpophalangeal joints (Model: BG 500, Mark-10 Corporation, New York, USA). Two maximal exertions were completed and the largest value was recorded.
Secondary Outcomes
- Wrist tracking task(Baseline (Week 0) and immediately post intervention (Week 4))
- wrist range of motion(Baseline (Week 0) and immediately post intervention (Week 4))
- Wolf Motor Function Test(Baseline (Week 0) and immediately post intervention (Week 4))
- Wolf Motor Function Test(Baseline (Week 0) and immediately post intervention (Week 4))
- Wrist tracking task(Baseline (Week 0) and immediately post intervention (Week 4))
- wrist range of motion(Baseline (Week 0) and immediately post intervention (Week 4))
Investigators
Michael Holmes
Associate Professor
Brock University