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PREPARE-IBD: Physician Responses to Disease Flares and Patient Adaptation in Relation to Events in Inflammatory Bowel Disease During COVID-19 Pandemic

Completed
Conditions
Coronavirus Infection
Inflammatory Bowel Diseases
Registration Number
NCT04410484
Lead Sponsor
Hull University Teaching Hospitals NHS Trust
Brief Summary

To find out what adaptations have been made by Inflammatory bowel disease physicians and patients in relation to therapies in flaring IBD patients during severe acute respiratory syndrome 2-COV and what the impact of these is on IBD patients with no symptomatic COVID-19 and in suspected/confirmed COVID-19. Also whether there any IBD related factors impacting the outcome of patients with COVID-19 symptoms or COVID-19 disease

Detailed Description

An observational, retrospective, case-controlled study to determine the status of IBD during development of COVID-19 symptoms/positive COVID-19. The aim is to describe the adaptations in therapies for active IBD during SARS COV 2 in patients with active IBD and positive or negative COVID-19 symptoms. It will evaluate IBD outcomes following development of COVID-19 symptoms / positive COVID-19 and determine any predictors of outcomes in IBD patients with COVID-19 symptoms / positive COVID-19 as well as determine the impact on IBD outcomes resulting from adaptations to treatments during COVID-19

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
3728
Inclusion Criteria
  • Patients with IBD +/- flare +/- COVID 19 positivity
Exclusion Criteria
  • Patients below 16
  • Patient with inactive IBD

Study & Design

Study Type
OBSERVATIONAL
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Flare of IBD needing change in therapy or surgery3 months
Secondary Outcome Measures
NameTimeMethod

Trial Locations

Locations (1)

Gastroenterology, Hull Royal Infirmary, Hull University Teaaching Hospitals NHS Trust

🇬🇧

Hull, United Kingdom

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