Acute Renal Insufficiency (ARI) Rate and Predictive Score of ARI in Hospitalized Patients for Acute Coronary Syndrome With ST-segment Elevation Needing Urgent Coronarography

• Conditions: Acute Renal Insufficiency; Acute Coronary Syndrome

• Registration Number: NCT04481126
• Lead Sponsor: Assistance Publique - Hôpitaux de Paris

Brief Summary

The primary objective of the study aims to evaluate frequence of acute renal insufficiency in patients with ST-segment elevation who need urgent coronary angiography in Ambroise Paré hospital.

The secondary objectives are:

* identify factors of risks associated with the occurrence of acute renal insufficiency after coronarography.

* establish a preprocedure score, predicting of acute renal insufficiency after urgent coronary angiography in patients with ST+ acute coronary syndrome.

Detailed Description

Not available

Study Timeline

• Study Start: 2020-07-01
• Study First Submitted: 2020-07-17
• Study First Submitted QC: 2020-07-17
• Study First Posted: 2020-07-22
• Status Verified: 2021-09
• Last Update Submitted: 2021-09-27
• Last Update Posted: 2021-09-28
• Primary Completion: 2022-12
• Study Completion: 2022-12

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 168

Inclusion Criteria

• patient aged ≥ 18 years;
• evocative symptoms of myocardiac ischemia: typical chest pain; ST-segment elevation and 1 mm in two consecutive peripheral leads and 2 mm in two consecutive precordial derivations, or appearance of a bloc of left branch of novo;
• need urgent coronarography;
• Covered by french social security scheme included CMU.

Exclusion Criteria

• dialysed patient for chronic renal insufficiency;
• cardio-resporatory arrest;
• cardiogenic choc state;
• prior emergency passage to hospital;
• patient under tutor, gardianship;
• patient covered by french AME scheme;
• pregnant women or breastfeeding;
• all medical, psychological or social situation which should influents the compliance to protocol according to investigator;
• patient refusal.

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
incidence of acute renal failure	at baselin and at 48 hours	Acute renal failure is defined as an increase in plasma creatinine of at least 26.5µmol/l within 48 hours, or an increase in plasma creatinine of at least 1.5 times plasma creatinine within 48hours of hospitalisation

Trial Locations

Locations (1)

Nephrology department, Ambroise Paré hospital, APHP; 🇫🇷 Boulogne-Billancourt, France