Acute Renal Insufficiency (ARI) Rate and Predictive Score of ARI in Hospitalized Patients for Acute Coronary Syndrome With ST-segment Elevation Needing Urgent Coronarography

Assistance Publique - Hôpitaux de Paris1 site in 1 country168 target enrollmentJuly 1, 2020

ConditionsAcute Renal Insufficiency Acute Coronary Syndrome

Overview

Phase: Not Applicable
Intervention: Not specified
Conditions: Acute Renal Insufficiency
Sponsor: Assistance Publique - Hôpitaux de Paris
Enrollment: 168
Locations: 1
Primary Endpoint: incidence of acute renal failure
Last Updated: 4 years ago

Overview Investigators Eligibility Criteria Outcomes Sites Similar Trials

Overview

Brief Summary

The primary objective of the study aims to evaluate frequence of acute renal insufficiency in patients with ST-segment elevation who need urgent coronary angiography in Ambroise Paré hospital.

The secondary objectives are:

identify factors of risks associated with the occurrence of acute renal insufficiency after coronarography.
establish a preprocedure score, predicting of acute renal insufficiency after urgent coronary angiography in patients with ST+ acute coronary syndrome.

Registry

clinicaltrials.gov

Start Date

July 1, 2020

End Date

December 2022

Last Updated

4 years ago

Study Type

Observational

Sex

All

Investigators

Sponsor

Assistance Publique - Hôpitaux de Paris

Responsible Party

Sponsor

Eligibility Criteria

Inclusion Criteria

•patient aged ≥ 18 years;
•evocative symptoms of myocardiac ischemia: typical chest pain; ST-segment elevation and 1 mm in two consecutive peripheral leads and 2 mm in two consecutive precordial derivations, or appearance of a bloc of left branch of novo;
•need urgent coronarography;
•Covered by french social security scheme included CMU.

Exclusion Criteria

•dialysed patient for chronic renal insufficiency;
•cardio-resporatory arrest;
•cardiogenic choc state;
•prior emergency passage to hospital;
•patient under tutor, gardianship;
•patient covered by french AME scheme;
•pregnant women or breastfeeding;
•all medical, psychological or social situation which should influents the compliance to protocol according to investigator;
•patient refusal.

Outcomes

Primary Outcomes

incidence of acute renal failure

Time Frame: at baselin and at 48 hours

Acute renal failure is defined as an increase in plasma creatinine of at least 26.5µmol/l within 48 hours, or an increase in plasma creatinine of at least 1.5 times plasma creatinine within 48hours of hospitalisation