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Clinical Trials/NCT05941260
NCT05941260
Completed
Not Applicable

Standardization of Prostatic Resection Operative Techniques by Virtual Computational Reconstruction and Computational Flow Dynamics

Ain Shams University1 site in 1 country15 target enrollmentJuly 15, 2023

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Prostate Hyperplasia
Sponsor
Ain Shams University
Enrollment
15
Locations
1
Primary Endpoint
computerized urodynamic module of the male urethra
Status
Completed
Last Updated
last year

Overview

Brief Summary

The enlargement of the prostate is responsible for voiding dysfunction in men, and especially elderly men. The primary surgical treatment for symptomatic benign prostatic hypertrophy (BPH) was transurethral resection of the prostate (TURP).

However, current resection techniques are predominantly experience-based and judgment-based, with little evidence to support the most effective portion of the prostate to be respected. So, the investigators plan through the study to construct a flow diagram to evaluate the amount of tissue needed to be resected to improve voiding flow dynamics.

Detailed Description

Benign prostatic hyperplasia (BPH) is an enlargement of the prostate gland that develops in men and is a common cause of voiding dysfunction in elderly patients. It is a major public health concern, causing high morbidity and substantial worsening of men's quality of life. (QOL) Transurethral resection of the prostate (TURP) is the standard surgical therapy for obstructive prostatic hypertrophy. Various techniques have been suggested for the systematic removal of the adenomatous tissue, all based on the principle that the resection should be done stepwise as bleeding is the surgeon's major problem, leading to loss of visual field and disorientation, it is imperative that resection and hemostasis should both be completed in one area of the prostatic fossa before the next area is tackled. With the development of new techniques for prostate resection that decreases perioperative morbidity, larger sizes of the prostate are being resected, and a new category of patients is considered eligible for such an intervention with a large prostate size of more than 80 gm. However, current resection techniques are predominantly experience-based and judgment-based, with little evidence to support the most effective portion of the prostate to be resected to give us the best voiding outcome postoperative. So, the investigators plan through this study to construct a flow diagram to evaluate the amount of tissue needed to be resected to improve voiding flow dynamics.

Registry
clinicaltrials.gov
Start Date
July 15, 2023
End Date
August 15, 2023
Last Updated
last year
Study Type
Observational
Sex
Male

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Ahmed Maher Gamil Ahmed Higazy

principle investigator

Ain Shams University

Eligibility Criteria

Inclusion Criteria

  • Age: above 50 years old, undergoing an elective endo-urological procedure

Exclusion Criteria

  • Neurogenic bladder
  • Previous prostate or urethral surgery
  • Associated urethral stricture

Outcomes

Primary Outcomes

computerized urodynamic module of the male urethra

Time Frame: 1 month from the time of video recording during surgery.

Is to formulate a computerized urodynamic module to simulate the bladder-urethral passage, evaluate urine flow, and predict the amount of needed tissue to be resected to improve patient voiding by a computerized module.

Study Sites (1)

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