Multi-institutional clinical phaseII trial of neoadjuvant chemotherapy with gemcitabine and cisplatin in patients with invasive urothelial carcinoma of the urinary bladder
Phase 2
Recruiting
- Conditions
- Muscle-invasive bladder cancer
- Registration Number
- JPRN-UMIN000003738
- Lead Sponsor
- ara Medical University Department of Urology
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 45
Inclusion Criteria
Not provided
Exclusion Criteria
1)Serious active infection 2)Temperature(<38) 3)Serious intercurrent medical or psychiatric illness 4)Prior malignancy [the patient has been disease free under 5 years] 5)Brain metastasis 6)Pleural effusion or ascites 7)Pericardial effusion 8)Varicella 9)peripheral neuropathy 10)Drug allergy or Pre-existing 11)If female of childbearing potential, pregnancy test is possitive 12)Others; based on the physicians' judgement
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Response rate of neoadjuvant GC(GEM+CDDP)chemotherpy in patients with invasive bladder cancer
- Secondary Outcome Measures
Name Time Method Safety, Overall survival period, Cancer-specific survival period, Progression-free survival period