A study of the efficacy of preoperative chemotherapy and radiation therapy for rectal cancer
Not Applicable
- Conditions
- rectal cancer
- Registration Number
- JPRN-UMIN000018563
- Lead Sponsor
- Tokyo Women's Medical University Hospital
- Brief Summary
The completion rate of CRT was high at 94% (n=29/31). The downstaging rate of CRT was 61% (n=19/31). The pathological complete response rate was 6.5% (n=2/31). Significant differences were observed in the 3-year local recurrence rate between the two groups (P<0.05).
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 40
Inclusion Criteria
Not provided
Exclusion Criteria
(1)Preoperative diagnosis of rectal cancer in M or MP and N0 Stage I (Japanese Classification of Colorectal Carcinoma the 7th edition) (2)Patients who principal investigator has determined to be inappropriate as a subject
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method 3-year local control rate
- Secondary Outcome Measures
Name Time Method (1)3-year over-all survival rate (2)Complete chemoradiotherapy rate (3)Postoperative complications rate