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Evaluation of the Effects of Levonorgestrel-releasing Intrauterine Device and Dydrogestreone on Quality of Life and Sexual Life in Patients With Abnormal Uterine Bleeding.

Conditions
Abnormal Uterine Bleeding
Interventions
Other: SF-36 Scores
Registration Number
NCT05474703
Lead Sponsor
Kanuni Sultan Suleyman Training and Research Hospital
Brief Summary

This study was retrospectively collected from patients who were diagnosed with abnormal uterine bleeding and received oral dydrogesterone therapy for at least six months or who were administered an intrauterine device containing levonorgestrel at least six months ago, and prospectively Short form 36 (P-36); It covers the comparison of the Quality of Life Scale and the Female Sexual Function Scale (FSFI) by asking over the phone.

Detailed Description

This study aimed to apply to the Gynecology and Obstetrics Clinic of Istanbul Health Sciences University Kanuni Sultan Süleyman Training and Research Hospital between August 2020 and December 2021, diagnosed with abnormal uterine bleeding between the ages of 18-45 and receive oral dydrogesterone treatment for at least six months or an intrauterine device releasing levonorgestrel. A total of 171 sexually active female patients who were treated were included. Of the patients participating in the study, 86 comprised two groups of patients who received LNG-IUD, and 85 received oral dydrogesterone treatment.

This study was retrospectively collected from patients who were diagnosed with abnormal uterine bleeding and received oral dydrogesterone therapy for at least six months or who had an intrauterine device containing levonorgestrel at least six months ago, and prospectively Short form 36 (P-36); It covers the comparison of the Quality of Life Scale and the Female Sexual Function Scale (FSFI) by asking over the phone.

Patients outside the age range of 18-45, sexually inactive patients, patients in pregnancy or postpartum, patients with known malignancy history or suspected malignancy, patients with abnormal smear results, patients with bleeding diathesis, patients using drugs that may cause vaginal bleeding, gynecological patients. Patients with any organic pathology that could explain bleeding on examination, patients with levonorgestrel-releasing intrauterine mediator dislocated, and patients who had previously received different treatments for abnormal uterine bleeding were not included.

Recruitment & Eligibility

Status
UNKNOWN
Sex
Female
Target Recruitment
171
Inclusion Criteria
  • Sexually active patients with abnormal uterine bleeding
  • Patients with no known malignancy history or suspected malignancy, patients with average smear results,
  • Patients without bleeding diathesis,
  • Patients using drugs that may cause vaginal bleeding,
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Exclusion Criteria
  • Sexually inactive patients
  • Patients in pregnancy or postpartum period,
  • Patients with a known history of malignancy or suspected malignancy, patients with abnormal smear results,
  • Patients with bleeding diathesis,
  • Patients using drugs that may cause vaginal bleeding, patients with any organic pathology to explain the bleeding in gynecological examination
  • Patients with a dislocated levonorgestrel-releasing intrauterine device
  • Patients who have previously received different treatments for abnormal uterine bleeding
Read More

Study & Design

Study Type
OBSERVATIONAL
Study Design
Not specified
Arm && Interventions
GroupInterventionDescription
AUK with DydrogestroneSF-36 ScoresPatients who applied for abnormal uterine bleeding and received oral dydrogesterone therapy for at least 6 months
AUK with Levonorgestrel releasing intrauterin deviceSF-36 ScoresPatients who applied for abnormal uterine bleeding and were administered levonorgestrel-releasing intrauterine device at least 6 months ago
Primary Outcome Measures
NameTimeMethod
Short Form- 36 scores (SF-36)6 months

The difference in quality of life between the two groups will be evaluated with the SF-36 scale.

Secondary Outcome Measures
NameTimeMethod
The Female Sexual Function Index FSFI scores6 months

Sexual life quality difference between the two groups will be evaluated with the FSFI scale.

Trial Locations

Locations (1)

Pinar Yalcin Bahat

🇹🇷

Istanbul, İ̇stanbul, Turkey

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