Re-infection Rates of Soil-transmitted Helminth Infections Among School-aged Children Following a Single or a 4-monthly Health Hygiene Education: an Open Label Clinical Trial
试验速览
- 阶段
- 不适用
- 入组人数
- 432
- 试验地点
- 1
- 主要终点
- The effectiveness of repeated health hygiene education on the reinfection rates of STHs among school-aged children
研究概览
简要总结
Soil-transmitted helminth (STH) infections caused by Ascaris lumbricoides, Trichuris trichiura, or hookworm, affect approximately 1.5 millions individuals primarily in tropical and subtropical regions. STHs infections have been associated with delay in growth and development in children. The prevalence in Indonesia varied from 45% to 65%, but in poor sanitation areas the prevalence can increased to 80%. World Health Organization currently recommends mass treatment with benzimidazoles and health hygiene education to control the disease. In this study we evaluated the effectiveness of single and four-monthly health hygiene education to STH reinfection rates among school-aged children in Mandailing Natal district, North Sumatera province, Indonesia.
详细描述
In this study we evaluate the prevalence of STH among school-aged children using Kato Katz examination prior to enrolment to the study. Two elementary schools in Mandailing Natal district, North Sumatera province, Indonesia have been selected and received either a single or repeated health hygiene education. Preliminary knowledge was also assessed using a questionnaire. Infected children received treatment of albendazole 400 mg for 3 days. Evaluation on reinfection status and STH knowledge is done at 4 month, 8 month and 12 months.
研究设计
- 研究类型
- Interventional
- 分配方式
- Non Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- Single (Participant)
入排标准
- 年龄范围
- 6 Years 至 15 Years（Child）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Children who are negative for STHs infection on Kato Katz examination following 3 days treatment of albendazole
排除标准
- •Parents who refused to participate in the study
- •Severe malnutrition
- •Co-infected with other helminth infections
结局指标
主要结局
The effectiveness of repeated health hygiene education on the reinfection rates of STHs among school-aged children
时间窗: 12 months
STH prevalence at 12 months
次要结局
- Knowledge of STHs prevention measures among school-aged children before and after intervention(12 months)
- Prevalence of STHs among school-aged children prior to intervention(STH prevalence at month 0)
研究者
Inke Nadia Diniyanti Lubis
Head of Tropical Medicine Master Programme
Universitas Sumatera Utara