Soil-transmitted Helminth Reinfection Rates After Single and Repeated School Hygiene Education

Not Applicable

• Conditions: Children, Only; Helminthiasis; Trichuris Infection; Ascaris Infection; Hookworm Infections
• Interventions: Behavioral: Health hygiene education

• Registration Number: NCT04227834
• Lead Sponsor: Universitas Sumatera Utara

Brief Summary

Soil-transmitted helminth (STH) infections caused by Ascaris lumbricoides, Trichuris trichiura, or hookworm, affect approximately 1.5 millions individuals primarily in tropical and subtropical regions. STHs infections have been associated with delay in growth and development in children. The prevalence in Indonesia varied from 45% to 65%, but in poor sanitation areas the prevalence can increased to 80%. World Health Organization currently recommends mass treatment with benzimidazoles and health hygiene education to control the disease. In this study we evaluated the effectiveness of single and four-monthly health hygiene education to STH reinfection rates among school-aged children in Mandailing Natal district, North Sumatera province, Indonesia.

Detailed Description

In this study we evaluate the prevalence of STH among school-aged children using Kato Katz examination prior to enrolment to the study. Two elementary schools in Mandailing Natal district, North Sumatera province, Indonesia have been selected and received either a single or repeated health hygiene education. Preliminary knowledge was also assessed using a questionnaire. Infected children received treatment of albendazole 400 mg for 3 days. Evaluation on reinfection status and STH knowledge is done at 4 month, 8 month and 12 months.

Study Timeline

• Study Start: 2019-03-04
• Primary Completion: 2019-03-06
• Status Verified: 2020-01
• Study First Submitted: 2020-01-04
• Study First Submitted QC: 2020-01-10
• Last Update Submitted: 2020-01-10
• Study First Posted: 2020-01-14
• Last Update Posted: 2020-01-14
• Study Completion: 2020-03-02

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 432

Inclusion Criteria

• Children who are negative for STHs infection on Kato Katz examination following 3 days treatment of albendazole

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Exclusion Criteria

• Parents who refused to participate in the study
• Severe malnutrition
• Co-infected with other helminth infections

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Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Single education	Health hygiene education	Single health hygiene education
Repeated education	Health hygiene education	Four-monthly health hygiene education

Primary Outcome Measures

Name	Time	Method
The effectiveness of repeated health hygiene education on the reinfection rates of STHs among school-aged children	12 months	STH prevalence at 12 months

Secondary Outcome Measures

Name	Time	Method
Knowledge of STHs prevention measures among school-aged children before and after intervention	12 months	A questionnaire used to evaluate the knowledge about STHs prevention
Prevalence of STHs among school-aged children prior to intervention	STH prevalence at month 0	Ascaris lumbricoides, Trichuris trichiura, hookworm infections at month 0

Trial Locations

Locations (1)

Singkuang sub-district, Mandailing Natal district; 🇮🇩 Panyabungan, North Sumatera, Indonesia