NCT03708653已完成不适用
Association Between Some Candidate Single Nucleotide Polymorphisms and Postherpetic Neuralgia
Second Affiliated Hospital, School of Medicine, Zhejiang University1 个研究点 分布在 1 个国家目标入组 181 人开始时间: 2018年4月1日最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 181
- 试验地点
- 1
- 主要终点
- correlation between pain SNPs and PHN
研究概览
简要总结
Postherpetic neuralgia (PHN) is a common condition and affecting 5 to 30% of the herpes zoster patients. In some cases, the pain remained refractory after first and second line treatment for herpes zoster. This suggests that there may be genetic variants that make some patients susceptible to PHN. Using saliva samples from herpes zoster patients the investigators are going to analyze the relationship between single nucleotide polymorphisms (SNPs) in genes that are known to be involved in pain and PHN.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 50 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Age more than 50 years
- •Clinically defined herpes zoster patients
排除标准
- •Patients not able to provide informed consent
结局指标
主要结局
correlation between pain SNPs and PHN
时间窗: At Enrollment
次要结局
未报告次要终点
研究者
研究点 (1)
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