Single Nucleotide Polymorphisms (SNPs) Associated With Postherpetic Neuralgia
Completed
- Conditions
- Postherpetic Neuralgia
- Registration Number
- NCT03708653
- Lead Sponsor
- Second Affiliated Hospital, School of Medicine, Zhejiang University
- Brief Summary
Postherpetic neuralgia (PHN) is a common condition and affecting 5 to 30% of the herpes zoster patients. In some cases, the pain remained refractory after first and second line treatment for herpes zoster. This suggests that there may be genetic variants that make some patients susceptible to PHN. Using saliva samples from herpes zoster patients the investigators are going to analyze the relationship between single nucleotide polymorphisms (SNPs) in genes that are known to be involved in pain and PHN.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 181
Inclusion Criteria
- Age more than 50 years
- Clinically defined herpes zoster patients
Exclusion Criteria
- Patients not able to provide informed consent
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method correlation between pain SNPs and PHN At Enrollment
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
The second affiliated hospital of Zhejiang University
🇨🇳Hangzhou, Zhejiang, China