NCT00541684已完成3 期
A Randomized, Double-Blind, Two Arm, Parallel Group Health Assessment Study of Losartan or Atenolol in Patients With Mild to Moderate Hypertension
适应症
相关药物
试验速览
- 阶段
- 3 期
- 状态
- 已完成
- 入组人数
- 143
- 主要终点
- number of sexual intercourse events in a 2-week period
研究概览
简要总结
The study will look at the effects of losartan or atenolol on frequency of sexual intercourse in subjects with newly diagnosed mild to moderate hypertension.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Double
入排标准
- 年龄范围
- 40 Years 至 49 Years（Adult）
- 性别
- Male
- 接受健康志愿者
- 否
入选标准
- •Newly diagnosed with mild to moderate hypertension\
- •Married male in stable heterosexual relationship
- •No prior history of sexual dysfunction
- •Satisfied with overall sex life
- •Patient's spouse is in close proximity for the study
- •Has had at least 2 but not more than 10 sexual intercourse events during the 2 week period prior to study start
- •Patient able to visit doctor in the morning of each scheduled visit
- •Able to complete the self administered health assessment questionnaire
排除标准
- •Hypertension due to cancer, history of heart or circulatory problems
- •History of mental disorder that might impair sexual function
- •History or presence of drug or alcohol abuse
- •Prior surgery for erectile dysfunction or other urological procedure
- •No penile implant or assist devices
- •History of chronic liver disease, history of diabetes
- •History of severe life-threatening diseases such as, cancer, AIDS or positive HIV test
- •Subjects with only 1 kidney
- •Mental handicap or legal incapacity
结局指标
主要结局
number of sexual intercourse events in a 2-week period
时间窗: 2 Weeks
次要结局
- sexual functioning score and overall sexual satisfaction score after 16 weeks(16 Weeks)
研究者
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